488703-59-9 Usage
Description
(R,R)-2-Carbamoylcyclohexanecarboxylic acid is a chiral carboxylic acid derivative with the molecular formula C9H15NO3. It features a carbamoyl group and a cyclohexane ring, which contribute to its unique structure and properties. (R,R)-2-Carbamoylcyclohexanecarboxylic acid is widely recognized for its role as a chiral building block in organic synthesis, particularly in the production of pharmaceuticals and other bioactive molecules. Its ability to create complex molecular structures with specific stereochemical arrangements makes it a valuable tool in chemical research and development.
Uses
Used in Pharmaceutical Industry:
(R,R)-2-Carbamoylcyclohexanecarboxylic acid is used as a chiral building block for the synthesis of pharmaceuticals. Its unique structure allows for the creation of complex molecular structures with specific stereochemistry, which is crucial for the development of effective and targeted drugs.
Used in Organic Synthesis:
In the field of organic synthesis, (R,R)-2-Carbamoylcyclohexanecarboxylic acid serves as a key intermediate for the production of various bioactive molecules. Its presence in the synthesis process can lead to the formation of compounds with desired biological activities and properties.
Used in Material Science:
(R,R)-2-Carbamoylcyclohexanecarboxylic acid has potential applications in the development of new materials. Its unique structure and properties can contribute to the creation of innovative materials with specific characteristics, useful in various industries.
Used in Chemical Process Development:
(R,R)-2-Carbamoylcyclohexanecarboxylic acid also plays a role in the development of new chemical processes. Its unique attributes can be harnessed to improve existing processes or to create new ones, enhancing the efficiency and effectiveness of chemical production.
Check Digit Verification of cas no
The CAS Registry Mumber 488703-59-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,8,7,0 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 488703-59:
(8*4)+(7*8)+(6*8)+(5*7)+(4*0)+(3*3)+(2*5)+(1*9)=199
199 % 10 = 9
So 488703-59-9 is a valid CAS Registry Number.
488703-59-9Relevant articles and documents
Enantiomerically pure β-amino acids: A convenient access to both enantiomers of trans-2-aminocyclohexanecarboxylic acid
Berkessel, Albrecht,Glaubitz, Katja,Lex, Johann
, p. 2948 - 2952 (2002)
Enantiomerically pure trans-2-aminocyclohexanecarboxylic acid is an important building block for helical β-peptides. We report here that this amino acid can be obtained from trans-cyclohexane-1,2-dicarboxylic acid in good yield by a simple one-pot procedure comprising cyclization to the anhydride, amide formation with ammonia, and a subsequent Hofmann-type degradation with phenyliodine(III) bis(trifluoroacetate) (PIFA) as the oxidant. The N-Fmoc- and N-BOC-protected derivatives were obtained by treatment of the amino acid with Fmoc-OSu and BOC2O, respectively. The N-BOC derivative could be prepared in even better overall yield by a one-pot procedure leading directly from trans-cyclohexane-1,2-dicarboxylic acid to the N-BOC-protected amino acid. Both enantiomers of the starting trans-1,2-cyclohexanedicarboxylic acid can be obtained easily and in large quantities by separating commercially available racemic trans-1,2-cyclohexanedicarboxylic acid using either (R)- or (S)-1-phenethylamine. X-ray crystallography of the diastereomerically pure salt obtained from (R)-1-phenethylamine revealed that the configuration of the diacid component is (1R,2R), and not (1S,2S) as reported in the literature. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
