489431-27-8

Basic information

• Product Name: Phosphonic acid, [2-[bis(phenylmethyl)amino]-2-oxoethyl]-, diphenyl ester
• CAS NO: 489431-27-8
• Molecular Formula: C28H26NO4P
• Molecular Weight: 471.492
• Mol File: 489431-27-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [2-[bis(phenylmethyl)amino]-2-oxoethyl]-, diphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [2-[bis(phenylmethyl)amino]-2-oxoethyl]-, diphenyl ester(489431-27-8)
• EPA Substance Registry System: Phosphonic acid, [2-[bis(phenylmethyl)amino]-2-oxoethyl]-, diphenyl ester(489431-27-8)

Safety Data

• Hazardous Substances Data: 489431-27-8(Hazardous Substances Data)

Upstream product

• 4712-55-4 diphenyl hydrogen phosphite 
• 2567-51-3 2-chloro-N,N-bis(phenylmethyl)acetamide 

Downstream Products

• 252667-35-9 (E)-4,4-dimethyl-N,N-bis(phenylmethyl)-2-pentenamide 

Relevant articles and documents

Synthesis of β-monosubstituted α,β-unsaturated amides with z-selectivity using diphenylphosphonoacetamides

The utility of diphenylphosphonoacetamides [(PhO)2P(O)CH 2CONRR′] as Horner-Wadsworth-Emmons reagents was examined with five different patterns of substitution upon the amide nitrogen atom (2a: R, R′ = CH2Ph; 2b: R = CH2Ph, R′ = H; 2c: R = Me, R′ = OMe; 2d: R, R′ = Ph; 2e: R, R′ = (CH2) 4). The reaction of 2a was found to be Z-selective for aromatic aldehydes with selectivities up to 95:5. Reagent 2b led to reasonable selectivity for both benzaldehyde (85:15) and 3-phenylpropionaldehyde (87:13), while 2c was somewhat effective for only the latter alkyl aldehyde (83:17). Compounds 2d and 2e exhibited slightly lower selectivities compared with 2a.