4927-43-9

Basic information

• Product Name: 5-BENZYL-5-PHENYLIMIDAZOLIDINE-2,4-DIONE
• Synonyms: 2,4-Imidazolidinedione, 5-phenyl-5-(phenylmethyl)-
• CAS NO: 4927-43-9
• Molecular Formula: C₁₆H₁₄N₂O₂
• Molecular Weight: 266.2946
• Mol File: 4927-43-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.24g/cm³
• Refractive Index: 1.608
• CAS DataBase Reference: 5-BENZYL-5-PHENYLIMIDAZOLIDINE-2,4-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BENZYL-5-PHENYLIMIDAZOLIDINE-2,4-DIONE(4927-43-9)
• EPA Substance Registry System: 5-BENZYL-5-PHENYLIMIDAZOLIDINE-2,4-DIONE(4927-43-9)

Safety Data

• Hazardous Substances Data: 4927-43-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H14N2O2/c19-14-16(18-15(20)17-14,13-9-5-2-6-10-13)11-12-7-3-1-4-8-12/h1-10H,11H2,(H2,17,18,19,20)/t16-/m1/s1

Upstream product

• 57-13-6 urea 
• 7570-85-6 trans-2,3-epoxy-1,3-diphenyl-1-propanone 
• 451-40-1 phenyl benzyl ketone 
• 151-50-8 potassium cyanide 
• 506-87-6 ammonium carbonate 
• 100-47-0 benzonitrile 
• 6921-34-2 benzylmagnesium chloride 
• 5411-12-1 chalcone epoxide 

Downstream Products

• 56594-95-7 2-Amino-2,3-diphenyl-propionsaeure 

Relevant articles and documents

Synthesis, structure, and solvatochromic properties of pharmacologically active 5-substituted 5-phenylhydantoins

A series of 5-substituted 5-phenylhydantoins was synthesized and their UV absorption spectra were recorded in the region 200-400 nm in selected solvents of different polarity. The effects of solvent dipolarity/polarizability and solvent-solute hydrogen-bonding interactions were analyzed by means of the linear solvation energy relationship concept proposed by Kamlet and Taft. The lipophilicities of the investigated hydantoins were estimated by calculation of their log P values. The quantitative relationship between the ratio of the contributions of specific solvent interactions and the corresponding lipophilicity parameter is discussed. The correlation equations were combined with the corresponding ED50 values and different physicochemical parameters to generate new equations that demonstrate the reasonable relationships between solute-solvent interactions and the structure-activity parameters. In order to determine a spectroscopic assignment of the absorption bands in different solvents, quantum chemical calculations were done. Springer-Verlag 2011.

Modified Bucherer-Bergs reaction for the one-pot synthesis of 5,5′-disubstituted hydantoins from nitriles and organometallic reagents

Diverse sets of 5,5′-disubstituted hydantoins can conveniently be made in moderate to good yields (40-92%) by a one-pot process involving treatment of aromatic, heteroaromatic or aliphatic nitriles with an organometallic reagent (RLi or RMgX) followed by