4946-22-9

Basic information

• Product Name: 4-(dimethylamino)thiophenol
• Synonyms: 4-(Dimethylamino)benzenethiol;4-Mercapto-N,N-dimethylaniline;4-(Dimethylamino)thiophenol 4-Mercapto-N,N-dimethylaniline
• CAS NO: 4946-22-9
• Molecular Formula: C₈H₁₁NS
• Molecular Weight: 153.24
• Mol File: 4946-22-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 28.45°C
• Boiling Point: 260°C(lit.)
• Flash Point: 107.1°C
• Appearance: /
• Density: 1.0676 (rough estimate)
• Vapor Pressure: 0.0183mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 10.14±0.24(Predicted)
• CAS DataBase Reference: 4-(dimethylamino)thiophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(dimethylamino)thiophenol(4946-22-9)
• EPA Substance Registry System: 4-(dimethylamino)thiophenol(4946-22-9)

Safety Data

• RTECS: DC1575000
• Hazardous Substances Data: 4946-22-9(Hazardous Substances Data)

Usage

Uses

4-(Dimethylamino)benzenethiol can be used as NTCP inhibitors to treat HBV and?/or HDV infection, hepatoprotection and amelioration of hypercholesterolemia, diabetes and inhibiting cancer.

InChI:InChI=1/C8H11NS/c1-9(2)7-3-5-8(10)6-4-7/h3-6,10H,1-2H3

Upstream product

• 7152-80-9 4-(dimethylamino)benzenethiocyanate 
• 500700-75-4 N,N-dimethyl-4-trichloromethylsulfanyl-aniline 
• 7732-18-5 water 
• 571167-29-8 3-(4-N,N-dimethylaminophenyl)-sulfanyl-propionic acid methyl ester 
• 7664-93-9 sulfuric acid 
• 19715-49-2 4-(dimethylamino)benzenesulfonyl chloride 
• 141-78-6 ethyl acetate 
• 7647-01-0 hydrogenchloride 
• 5397-29-5 4-(N,N-dimethylamino)phenyl disulfide 
• 160855-20-9 N-(N',N'-dimethyl-4-aminophenylthio)phthalimide 
• 13190-50-6 4-dimethylaminophenyllithium 
• 925-89-3 Prop-1-en-1-thiol 
• 854695-59-3 S-(4-dimethylamino-phenyl)-N,N'-diphenyl-isothiourea 
• 7664-41-7 ammonia 

Downstream Products

• 23094-82-8 (4-dimethylamino-phenyl)-(tetra-O-acetyl-1-thio-β-D-glucopyranoside) 
• 63116-10-9 3-Nitro-4'-dimethylaminodiphenyldisulfid 
• 63116-13-2 4-(N,N-dimethylamino)phenyl 4'-nitrophenyl disulfide 
• 63116-22-3 4-Dimethylamino-4'-bromdiphenyldisulfid 
• 69064-55-7 C₂₅H₃₁N₃S₃ 
• 57251-87-3 C₁₈H₂₄N₂S₂ 
• 57251-88-4 C₁₈H₂₄N₂O₂S₂ 
• 110873-04-6 N,N',N''-(2,2':6',2''-terpyridine)(4-dimethylaminobenzenethiolato)platinum(II) chloride 
• 63116-18-7 2,4-Dinitro-4'-dimethylaminodiphenyldisulfid 
• 63116-20-1 4-Dimethylamino-4'-methyldiphenyldisulfid 
• 101112-65-6 N,N-dimethyl-4-(4-nitro-benzylsulfanyl)-aniline 
• 5397-29-5 4-(N,N-dimethylamino)phenyl disulfide 
• 106365-95-1 2-(4-dimethylaminophenylthio)benzoic acid 
• 13512-02-2 S-(4-dimethylaminophenyl)-N,N-dimethylthiocarbamate 

Relevant articles and documents

Imposing Latency in Ruthenium Sulfoxide-Chelated Benzylidenes: Expanding Opportunities for Thermal and Photoactivation in Olefin Metathesis

Herein we show the design and synthesis of an electron-rich, sulfoxide-chelated, ruthenium benzylidene. In contrast to previously reported sulfoxide-chelated ruthenium benzylidenes, this complex is more stable in a cis-dichloro conformation and is thus latent in typical olefin metathesis reactions. The complex was characterized by NMR, UV-vis, and X-ray spectroscopy, alongside density functional theory computations. The latent precatalyst could be activated thermally and, depending on the solvent, by UV-C or visible light. In addition, an original "thermo-chromatic" orthogonal sequence was developed, further improved by the use of a thioether chelated complex, where a divergent two-step synthesis can lead to a dihydrofuran or a dihydropyran depending only on the order by which the different stimuli, heat or light, are applied.

HISTONE DEACETYLASE INHIBITORS

The present invention provides histone deacetylase inhibitors of general formula (I), process for the preparation of such compounds and uses of the compounds in medicine.

Polymerisation inhibitor

A monomer composition, stabilized against premature polymerization, comprising: a) an ethylenically unsaturated monomer or mixture of monomers polymerizable by free radical initiation, and b) an effective amount, sufficient to inhibit premature polymerization of component (a) of a mixture of: i) 1 to 99% by weight, based on the total weight of components (i) and (ii), of a mixture of at least one aromatic amine and at least one organic acid in a molar ratio of 10:1 to 1:10, and ii) 99 to 1% by weight, based on the total weight of components (i) and (ii), of at least one stable radical compound.