49609-15-6

Basic information

• Product Name: 2-Chloro-7-Methoxyquinoline
• Synonyms: 2-Chloro-7-Methoxyquinoline;QUINOLINE, 2-CHLORO-7-METHOXY-
• CAS NO: 49609-15-6
• Molecular Formula: C₁₀H₈ClNO
• Molecular Weight: 193.62962
• Mol File: 49609-15-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 97-98 °C
• Boiling Point: 145 °C(Press: 0.6 Torr)
• Appearance: /
• Density: 1.267±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.65±0.50(Predicted)
• CAS DataBase Reference: 2-Chloro-7-Methoxyquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-7-Methoxyquinoline(49609-15-6)
• EPA Substance Registry System: 2-Chloro-7-Methoxyquinoline(49609-15-6)

Safety Data

• Hazardous Substances Data: 49609-15-6(Hazardous Substances Data)

Usage

General Description

2-Chloro-7-Methoxyquinoline is a chemical compound with the molecular formula C10H7ClNO. It is a member of the quinoline family and contains a chloro and methoxy group at specific positions on the quinoline ring. 2-Chloro-7-Methoxyquinoline is used in various research and industrial applications, including as a precursor in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential biological activities, including its antimicrobial and anticancer properties. Overall, 2-Chloro-7-Methoxyquinoline is a versatile compound with a range of potential uses in various scientific and industrial fields.

Upstream product

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• 23981-26-2 7-methoxyquinolin-2(1H)-one 
• 15116-41-3 N-(3-methoxyphenyl)cinnamamide 
• 536-90-3 m-Anisidine 

Downstream Products

• 375358-19-3 2-chloroquinoline-7-ol 
• 1013060-14-4 C₂₅H₃₂N₄O₂ 
• 1013060-11-1 C₂₄H₃₀N₄O₂ 
• 1013060-08-6 C₂₃H₂₈N₄O₂ 

Relevant articles and documents

BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS

Described herein are compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables Ar, X, R1, R3, R 4, Y1, Y2, n and p are as defined herein.

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II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-{4-[(7-chloro-2-quinoxalinyl)oxylphenoxy}propionic acid (XK469)

XK469 (1) is among the most highly and broadly active antitumor agents to have been evaluated in our laboratories. Subsequent developmental studies led to the entry of (R)-(+) 1 (NSC 698215) into phase 1 clinical trials (NIH UO1-CA62487). The antitumor me