49781-48-8

Basic information

• Product Name: 2,2-DIFLUOROPROPIONAMIDE
• Synonyms: 2,2-DIFLUOROPROPIONAMIDE;2,2-Difluoropropionamide 97%;2,2-Difluoropropionamide97%;2,2-difluoropropanaMide
• CAS NO: 49781-48-8
• Molecular Formula: C3H5F2NO
• Molecular Weight: 109.07
• Mol File: 49781-48-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 67
• Boiling Point: 212℃
• Flash Point: 82℃
• Appearance: /
• Density: 1.214
• CAS DataBase Reference: 2,2-DIFLUOROPROPIONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIFLUOROPROPIONAMIDE(49781-48-8)
• EPA Substance Registry System: 2,2-DIFLUOROPROPIONAMIDE(49781-48-8)

Safety Data

• Hazardous Substances Data: 49781-48-8(Hazardous Substances Data)

Usage

General Description

2,2-Difluoropropionamide is a chemical compound with the formula C3H5F2NO. It is a colorless liquid at room temperature and is often used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Due to its fluoroalkyl group, it exhibits unique chemical and physical properties that make it valuable in organic synthesis. It is also used as a solvent and as a reagent in various chemical reactions. However, it is important to handle this compound with care, as it is toxic and can cause irritation to the skin, eyes, and respiratory system upon exposure. Additionally, proper safety measures, such as wearing protective clothing and working in a well-ventilated area, should be taken when handling 2,2-Difluoropropionamide.

Upstream product

• 79-37-8 oxalyl dichloride 
• 373-96-6 2,2-difluoropropanoic acid 

Downstream Products

• 49781-49-9 2,2-difluoropropionitrile 

Relevant articles and documents

Synthesis method and application of 4-oxo-trans-2-hexenal analogue

The invention discloses a synthesis method and application of a 4-oxo-trans-2-hexenal analogue, and belongs to the technical field of biological prevention and control. The analogues comprise 5-methyl-4-oxo-trans-2-hexenal, 5, 5-difluoro-4-oxo-trans-2-hexenal, 4-oxo-trans-2-hexenoic acid, 4-oxo-trans-2-hexenol and 4-hydroxy-trans-2-hexenal. One or more of the five compounds completely replace 4-oxo-trans-2-hexenal in sex pheromone components of apolygus lucorum, lygus pratensis and apolygus lucorum. The synthesis methods of the 5-methyl-4-oxo-trans-2-hexenal and the 5, 5-difluoro-4-oxo-trans-2-hexenal are found for the first time, the application composition can significantly reduce the release rate of the lure, prolong the trapping time and save the cost, the problem that the 4-oxo-trans-2-hexenal is unstable in the field can be avoided, and the application range of the 5-methyl-4-oxo-trans-2-hexenal is widened. Male insects such as apolygus lucorum, herbage miridae and apolygus lucorum can be trapped and killed more effectively.

Substituted 1,3-thiazole compounds, their production and use

(1) A 1,3-thiazole compound of which the 5-position is substituted with a 4-pyridyl group having a substituent including no aromatic group or (2) a 1,3-thiazole compound of which the 5-position is substituted with a pyridyl group having at the position adjacent to a nitrogen atom of the pyridyl group a substituent including no aromatic group has an excellent p38 MAP kinase inhibitory activity.