49787-00-0

Basic information

• Product Name: 4,N-DIHYDROXY-BENZAMIDINE
• Synonyms: N',4-DIHYDROXYBENZENECARBOXIMIDAMIDE;4,N-DIHYDROXY-BENZAMIDINE;4-HYDROXY-BENZAMIDINE OXIME;BenzenecarboxiMidaMide,N,4-dihydroxy-;N,4-Dihydroxy-benzimidamide
• CAS NO: 49787-00-0
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.15
• Product Categories: pharmacetical
• Mol File: 49787-00-0.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 390.309 °C at 760 mmHg
• Flash Point: 189.852 °C
• Appearance: /
• Density: 1.35 g/cm³
• Vapor Pressure: 7.82E-05mmHg at 25°C
• Refractive Index: 1.657
• CAS DataBase Reference: 4,N-DIHYDROXY-BENZAMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,N-DIHYDROXY-BENZAMIDINE(49787-00-0)
• EPA Substance Registry System: 4,N-DIHYDROXY-BENZAMIDINE(49787-00-0)

Safety Data

• Hazardous Substances Data: 49787-00-0(Hazardous Substances Data)

Usage

General Description

4,N-Dihydroxybenzamidine is a chemical compound that belongs to the class of benzamidines. It is a derivative of hydroxybenzamidine and contains two hydroxyl groups attached to the benzene ring. 4,N-DIHYDROXY-BENZAMIDINE is commonly used in chemical research and as a reagent in biochemical studies. It has been found to exhibit inhibitory activity against a range of enzymes, particularly serine proteases such as trypsin and chymotrypsin. Its structure and properties make it a valuable tool in the study of enzyme kinetics and inhibition, as well as in the development of potential pharmaceutical compounds.

InChI:InChI=1/C7H8N2O2/c8-7(9-11)5-1-3-6(10)4-2-5/h1-4,9,11H,8H2

Upstream product

• 767-00-0 4-cyanophenol 

Downstream Products

• 49787-05-5 4-[5-(2-chloro-phenyl)-[1,2,4]oxadiazol-3-yl]-phenol 
• 5509-32-0 4-(5-Chloromethyl-[1,2,4]oxadiazol-3-yl)-phenol 
• 49787-02-2 4-(5-methyl-1,2,4-oxadiazol-3-yl)phenol 
• 49787-04-4 4-(5-benzyl-[1,2,4]oxadiazol-3-yl)-phenol 
• 49787-03-3 4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-phenol 
• 40678-80-6 4-(5-pyridin-3-yl-[1,2,4]oxadiazol-3-yl)-phenol 
• 1038982-05-6 4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)phenol 
• 136125-27-4 4-(1,2,4-oxadiazol-3-yl)phenol 

Relevant articles and documents

Synergism of a novel 1,2,4-oxadiazole-containing derivative with oxacillin against methicillin-resistant staphylococcus aureus

Staphylococcus aureus is an important opportunistic pathogen that causes many infections in humans and animals. The inappropriate use of antibiotics has favored the diffusion of methicillin-resistant S. aureus (MRSA), nullifying the efforts undertaken in

SSAO INHIBITOR

The present invention provides an SSAO inhibitor and an application thereof in preparing a drug for treating a disease related to SSAO. In particular, the present invention provides a compound shown in formula (IV) and a pharmaceutically acceptable salt thereof.

Synthesis of novel mono and bis nitric oxide donors with high cytocompatibility and release activity

Four compounds bearing amidoxime functions were synthetized: (1) 2a,b bearing an aromatic amidoxime function, (2) 2c bearing an aliphatic amidoxime function, and (3) 2d bearing aromatic and aliphatic amidoximes functions. The ability of these compounds to