50-10-2

Basic information

• Product Name: Oxyphenonium bromide
• Synonyms: ba-5473;c5473;diethyl(2-hydroxyethyl)methylammoniumbromidealpha-phenylcyclohexaneglycolat;oxifenon;oxyfenon;oxyphenon;2-(alpha-cyclohexylmandeloyloxy)ethyldiethyl(methyl)ammonium bromide;2-[(Cyclohexylhydroxyphenylacetyl)oxy]-N,N,-diethyl-N-methylethylammonium bromide
• CAS NO: 50-10-2
• Molecular Formula: Br*C₂₁H₃₄NO₃
• Molecular Weight: 428.4
• EINECS: 200-010-7
• Product Categories: ANTRENYL
• Mol File: 50-10-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 189-194° from ethyl acetate + alc
• Appearance: /
• Density: 1.2584 (rough estimate)
• Refractive Index: 1.6200 (estimate)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: Oxyphenonium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: Oxyphenonium bromide(50-10-2)
• EPA Substance Registry System: Oxyphenonium bromide(50-10-2)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36
• WGK Germany: 3
• RTECS: BP7625000
• Hazardous Substances Data: 50-10-2(Hazardous Substances Data)

Usage

Uses

anticholinergic, anticonvulsant

Therapeutic Function

Anticholinergic, Spasmolytic

Safety Profile

Poison by ingestion, intramuscular, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: change in heart rate. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Brí.

InChI:InChI=1/C21H34NO3/c1-4-22(3,5-2)16-17-25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6,8-9,12-13,19,24H,4-5,7,10-11,14-17H2,1-3H3/q+1

Upstream product

• 3570-96-5 demethyloxyphenonium 
• 931-50-0 cyclohexylmagnesium bromide 
• 4335-77-7 cyclohexylmandelic acid 
• 31197-69-0 ethyl 2-cyclohexyl-2-hydroxy-2-phenylacetate 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 74-83-9 methyl bromide 

Relevant articles and documents

Quantitative estimation of the bitter taste intensity of oxyphenonium bromide reduced by cyclodextrins from electromotive force measurements

The bitter taste of oxyphenonium bromide, an antiacetylcholine drug, is suppressed by cyclodextrins. The extent of the suppression can be predicted from the electromotive force measurements with an oxyphenonium bromide- selective electrode. The relationship between the bitter taste intensity and the electromotive force holds true, regardless of the kind and concentration of natural and modified cyclodextrins. This result is explicable on the basis of the observation that both the bitter taste and the electric potential are determined by the concentration of free oxyphenonium bromide. Some implications and limitations of the present approach are discussed.