500317-68-0Relevant articles and documents
A mild, enantioselective synthesis of (R)-salmeterol via sodium borohydride-calcium chloride asymmetric reduction of a phenacyl phenylglycinol derivative
Bream, Robert N.,Ley, Steven V.,McDermott, Benjamin,Procopiou, Panayiotis A.
, p. 2237 - 2242 (2002)
A short and efficient enantioselective route to (R)-salmeterol involving asymmetric reduction of a phenylglycinyl ketone derivative followed by reductive amination of the resulting amino alcohol and hydrogenolysis is described.