500898-54-4

Basic information

• Product Name: Benzenamine, 2-[(2-chloro-6-nitrophenyl)thio]-6-methyl-
• CAS NO: 500898-54-4
• Molecular Formula: C13H11ClN2O2S
• Molecular Weight: 294.762
• Mol File: 500898-54-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-[(2-chloro-6-nitrophenyl)thio]-6-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-[(2-chloro-6-nitrophenyl)thio]-6-methyl-(500898-54-4)
• EPA Substance Registry System: Benzenamine, 2-[(2-chloro-6-nitrophenyl)thio]-6-methyl-(500898-54-4)

Safety Data

• Hazardous Substances Data: 500898-54-4(Hazardous Substances Data)

Upstream product

• 3209-22-1 1,2-Dichloro-3-nitrobenzene 
• 76462-17-4 2-methyl 6-mercapto aniline 

Downstream Products

• 500898-63-5 N-[2-(2-chloro-6-nitro-phenylsulfanyl)-6-methyl-phenyl]-formamide 

Relevant articles and documents

Synthesis of 1- and 3-methyl phenothiazines

Synthesis of 1-methyl/3-methyl phenothiazines is reported by Smiles rearrangement of 2-formamido-3-methyl/5-methyl-2′-nitro diphenylsulfides. The latter were obtained by the condensation of 2-amino-3-methyl/5-methylbenzenethiols with o-halonitrobenzenes followed by formylation. However 2-amino-3-methyl/5-methylbenzenethiols on condensation with halonitrobenzenes containing a nitrogroup at ortho positions to the reactive halogen atom directly yields 9-nitrophenothiazines as Smiles rearrangement and ring closure occur simultaneously in situ due to combined resonance and inductive effect reinforced by two nitrogroups.