501927-29-3 Usage
Description
MN-25-2-methyl derivative is a cannabinoid (CB) receptor ligand with Ki values of 8 and 29 nM at the central CB1 receptor and peripheral CB2 receptor, respectively. This product is intended for forensic and research applications.
Uses
MN-25, is a synthetic cannabinoid (CB) with greater affinity for the peripheral CB2 receptor (Ki = 11 nM) than for the central CB1 receptor (Ki = 245 nM). Synthetic Cannabinoids
Check Digit Verification of cas no
The CAS Registry Mumber 501927-29-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,1,9,2 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 501927-29:
(8*5)+(7*0)+(6*1)+(5*9)+(4*2)+(3*7)+(2*2)+(1*9)=133
133 % 10 = 3
So 501927-29-3 is a valid CAS Registry Number.
501927-29-3Relevant articles and documents
C-3 Amido-indole cannabinoid receptor modulators
Hynes Jr., John,Leftheris, Katerina,Wu, Hong,Pandit, Chennagiri,Chen, Ping,Norris, Derek J.,Chen, Bang-Chi,Zhao, Rulin,Kiener, Peter A.,Chen, Xiaorong,Turk, Lori A.,Patil-Koota, Vina,Gillooly, Kathleen M.,Shuster, David J.,McIntyre, Kim W.
, p. 2399 - 2402 (2007/10/03)
C-3 Amido-indoles were found to selectively bind to the CB2 receptor. SAR studies led to optimized compounds with excellent in vivo potency against LPS induced TNF-α release in murine models of cytokine production.
