502496-34-6 Usage
General Description
4-BROMO-2-FLUORO-6-NITROTOLUENE is a chemical compound with the molecular formula C7H5BrFNO2. It is a pale yellow to brown crystalline solid with a molecular weight of 215.02 g/mol. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. This chemical is also used in the manufacturing of dyes and pigments. It is important to note that 4-BROMO-2-FLUORO-6-NITROTOLUENE should be handled with care as it may pose hazards to human health and the environment if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 502496-34-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,2,4,9 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 502496-34:
(8*5)+(7*0)+(6*2)+(5*4)+(4*9)+(3*6)+(2*3)+(1*4)=136
136 % 10 = 6
So 502496-34-6 is a valid CAS Registry Number.
502496-34-6Relevant articles and documents
INHIBITORS OF KRAS G12C
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Page/Page column 292, (2015/04/28)
Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I): or a pharmaceutically acceptable salt, tautomer, prodrug or stereoisomer thereof, wherein R1, R2a, R3a, R3b, R4a, R4b, G1, G2, L1, L2, m1, m2, A, B, W, X, Y, Z and E are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of G12C mutant KRAS protein for treatment of disorders, such as cancer, are also provided.
