502496-36-8

Basic information

• Product Name: 3-Bromo-5-fluoro-2-methylaniline
• Synonyms: 3-Bromo-5-fluoro-2-methylaniline;3-Bromo-5-fluoro-2-methylbenzenamine;3-Bromo-5-fluoro-2-methylphenylamine;BenzenaMine, 3-broMo-5-fluoro-2-Methyl-;2-Methyl-3-bromo-5-fluoroaniline
• CAS NO: 502496-36-8
• Molecular Formula: C₇H₇BrFN
• Molecular Weight: 204.0395832
• Mol File: 502496-36-8.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 259℃
• Flash Point: 110℃
• Appearance: /
• Density: 1.589
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.36±0.10(Predicted)
• CAS DataBase Reference: 3-Bromo-5-fluoro-2-methylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-5-fluoro-2-methylaniline(502496-36-8)
• EPA Substance Registry System: 3-Bromo-5-fluoro-2-methylaniline(502496-36-8)

Safety Data

• Hazardous Substances Data: 502496-36-8(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-fluoro-2-methylaniline is a chemical compound with the molecular formula C7H7BrFN. It is a fluorescent and aromatic compound that is used in various chemical and pharmaceutical applications. 3-Bromo-5-fluoro-2-methylaniline is a derivative of aniline, and it contains a bromine atom, a fluorine atom, and a methyl group attached to the aromatic ring. 3-Bromo-5-fluoro-2-methylaniline has potential uses in organic synthesis, pharmaceutical drug development, and as a building block for the synthesis of other chemical compounds. Due to its unique structure and properties, this compound is of interest to researchers and scientists in the fields of chemistry, pharmaceuticals, and material science.

Upstream product

• 446-10-6 2-nitro-4-fluorotoluene 
• 502496-33-5 1-bromo-5-fluoro-2-methyl-3-nitrobenzene 
• 367-29-3 3-fluoro-6-methylaniline 

Downstream Products

• 1418128-33-2 5-fluoro-2-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine 
• 1418128-70-7 N-(3-bromo-5-fluoro-2-methyl-phenyl)-3-fluoro-terephthalamic acid methyl ester 
• 1184297-93-5 1-(3-bromo-5-fluoro-2-methyl-phenyl)-pyrrolidin-2-one 
• 885698-71-5 6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 

Relevant articles and documents

Aromatic amine derivative organic electroluminescent material and device thereof

The invention discloses an aromatic amine derivative organic electroluminescent material and a device thereof. The compound is a pyrene compound substituted with an aromatic amine, wherein the compound has a substituted or unsubstituted (hetero) aryl group and a pyrene compound substituted or unsubstituted aromatic amine structure of a (hetero) aryl group, which may be used as a light emitting material in an organic electroluminescent device. These novel compounds can provide better device performance, such as higher external quantum efficiency and narrower half-peak widths, and the like.

COMPOUNDS AND METHODS FOR TARGETED DEGRADATION OF KRAS

Bifunctional compounds, which find utility as modulators of Kirsten ras sarcoma protein (KRas or KRAS), are described herein. In particular, the hetero-bifunctional compounds of the present disclosure contain on one end a moiety that binds to the Von Hippel-Lindau E3 ubiquitin ligase and on the other end a moiety which binds KRas, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The heterobifunctional compounds of the present disclosure exhibit a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aberrant regulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

(R)-3-(CHLORO-5-FLUORO-2-((4-(1H-PYRAZOL-1-YL)-2-METHYLQUINOLIN-8-YLOXY)METHYL)PHENYL)MORPHOLINE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ (BK) B2 RECEPTOR ANTAGONIST FOR TREATING SKIN DISEASES

The invention relates to a compound according to general formula (I), which acts as a bradykinin (BK) B2 receptor antagonist; to a pharmaceutical composition containing one or more of the compound(s) of the invention; to a combination preparation containi