50304-31-9 Usage
General Description
(17beta)-17-hydroxy-3-methoxyestra-1,3,5(10)-triene-17-carbonitrile, also known as 17-beta-estradiol-3-methyl-ether-17-cyanohydrin, is a synthetic chemical compound with a complex chemical structure. It is a derivative of the hormone 17-beta-estradiol, which is a form of estrogen. The compound has a hydroxy group at the 17th position, a methoxy group at the 3rd position, and a nitrile group at the 17th position. This chemical is important in the field of pharmacology and medicine as it serves as a precursor for the synthesis of various pharmaceuticals and research chemicals. It may also have potential applications in hormone replacement therapy and the treatment of various medical conditions related to hormonal imbalances.
Check Digit Verification of cas no
The CAS Registry Mumber 50304-31-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,0 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 50304-31:
(7*5)+(6*0)+(5*3)+(4*0)+(3*4)+(2*3)+(1*1)=69
69 % 10 = 9
So 50304-31-9 is a valid CAS Registry Number.
50304-31-9Relevant articles and documents
An efficient synthesis of 3-methoxy-19-norpregna-1,3,5(10),16-tetraen-20-one
Kuznetsov, Yu. V.,Levina,Shashkov,Zavarzin
, p. 2112 - 2120 (2018)
An efficient preparative method for the synthesis of 3-methoxy-19-norpregna-1,3,5(10), 16-tetraen-20-one was suggested. This compound is a key intermediate product in the preparation of 3,20-dihydroxy-19-norpregnatrienes, antagonists of estrogen receptor and cytotoxic agents. The reaction of 16-dehydro-17-carbonitrile (obtained in two steps from estrone methyl ether) with methyl magnesium halides gave the target product in high yield. While studying this reaction, we isolated and characterized an unusual steroid dimer, a fused 16,17-pyridinosteroid substituted in the hetero ring of the second steroid molecule. A mechanism of its formation was suggested.
