503184-36-9Relevant articles and documents
Synthesis and structure-activity relationships of pyrido[3,2-b]pyrazin- 3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonists
Dzierba, Carolyn D.,Sielecki, Thais M.,Arvanitis, Argyrios G.,Galka, Amy,Johnson, Tricia L.,Takvorian, Amy G.,Rafalski, Maria,Kasireddy-Polam, Padmaja,Vig, Shikha,Dasgupta, Bireshwar,Zhang, Ge,Molski, Thaddeus F.,Wong, Harvey,Zaczek, Robert C.,Lodge, Nicholas J.,Combs, Andrew P.,Gilligan, Paul J.,Trainor, George L.,Bronson, Joanne J.,MacOr, John E.
scheme or table, p. 4986 - 4989 (2012/08/28)
Pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones were evaluated as corticotropin-releasing factor-1 receptor antagonists. The synthesis, SAR studies and pharmacokinetic evaluation of these analogs are described herein.
