504408-80-4

Basic information

• Product Name: 2,4-DIPYRIDIN-3-YLPYRIMIDINE
• Synonyms: 2,4-DIPYRIDIN-3-YLPYRIMIDINE;2,4-bis(pyridin-3-yl)pyrimidine
• CAS NO: 504408-80-4
• Molecular Formula: C14H10N4
• Molecular Weight: 234.256
• Mol File: 504408-80-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 359.367 °C at 760 mmHg
• Flash Point: 158.194 °C
• Appearance: /
• Density: 1.214 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 2,4-DIPYRIDIN-3-YLPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIPYRIDIN-3-YLPYRIMIDINE(504408-80-4)
• EPA Substance Registry System: 2,4-DIPYRIDIN-3-YLPYRIMIDINE(504408-80-4)

Safety Data

• Hazardous Substances Data: 504408-80-4(Hazardous Substances Data)

Usage

General Description

2,4-Dipyridin-3-ylpyrimidine is a chemical compound with the molecular formula C10H7N5. It is a pyridine derivative consisting of two pyridine rings and a pyrimidine ring. 2,4-DIPYRIDIN-3-YLPYRIMIDINE has potential applications in pharmaceutical research and drug development due to its ability to modulate the activity of specific enzymes and proteins in the human body. Additionally, it is used as a building block in the synthesis of bioactive molecules and functional materials. The chemical structure and properties of 2,4-dipyridin-3-ylpyrimidine make it a valuable tool in the study and development of therapeutic agents for various medical conditions.

InChI:InChI=1/C14H10N4/c1-3-11(9-15-6-1)13-5-8-17-14(18-13)12-4-2-7-16-10-12/h1-10H

Upstream product

• 1570-48-5 1-(pyridin-3-yl)propan-1-one 
• 7356-60-7 pyridine-3-carboxamidine hydrochloride 
• 3934-20-1 2,6-Dichloropyrimidine 
• 52770-25-9 pyridine-3-yl magnesium chloride 

Relevant articles and documents

Preparation method of polysubstituted pyrimidine

The invention belongs to the field of chemical synthesis, and particularly relates to a preparation method of polysubstituted pyrimidine. The method comprises the following step that amidine hydrochloride and a propiophenone compound react in the presence of an iron source compound, 1,10-phenanthroline and tetramethyl piperidine nitric oxide to obtain polysubstituted pyrimidine, wherein propiophenone or a propiophenone derivative is adopted as the propiophenone compound. According to the method, polysubstituted pyrimidine can be generated through a reaction by taking the propiophenone compound and amidine hydrochloride as reacting raw materials under combined promotion of the iron source compound, 1,10-phenanthroline and the tetramethyl piperidine nitric oxide; a strong alkaline or strong acidic environment is not needed, the reaction conditions are simple and mild, and the yield of polysubstituted pyrimidine is high. Experiment results show that the maximum yield of polysubstituted pyrimidine prepared through the method can reach 93% or above.

Aryl-aryl bonds formation in pyridine and diazine series. Diazines part 41

The synthesis of several symmetrical polyaromatic compounds with pyridine or diazine units has been achieved by homocoupling of aryl halides with Pd(OAc)2 as catalyst. Cross-coupling reactions of aryl Grignard reagents with Fe(acac)3 as catalyst allowed the synthesis of various unsymmetrical polyaryl- or polyheteroaryl compounds with π-deficient rings.