50586-62-4

Basic information

• Product Name: cyanomethyl diethyl phosphate
• Synonyms: cyanomethyl diethyl phosphate;Phosphoric acid (cyanomethyl)diethyl ester
• CAS NO: 50586-62-4
• Molecular Formula: C₆H₁₂NO₄P
• Molecular Weight: 193.137541
• EINECS: 256-628-2
• Mol File: 50586-62-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 264.1°C at 760 mmHg
• Flash Point: 113.5°C
• Appearance: /
• Density: 1.176g/cm³
• Vapor Pressure: 0.00992mmHg at 25°C
• Refractive Index: 1.423
• CAS DataBase Reference: cyanomethyl diethyl phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: cyanomethyl diethyl phosphate(50586-62-4)
• EPA Substance Registry System: cyanomethyl diethyl phosphate(50586-62-4)

Safety Data

• Hazardous Substances Data: 50586-62-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H12NO4P/c1-3-9-12(8,10-4-2)11-6-5-7/h3-4,6H2,1-2H3

Upstream product

• 107-14-2 chloroacetonitrile 
• 122-52-1 triethyl phosphite 
• 78-40-0 triethyl phosphate 

Downstream Products

• 131079-29-3 2-(2,2-dimethylethyl)butenedinitrile 
• 167375-71-5 [4‐(trifluoromethoxy)phenyl]prop‐2‐enenitrile 
• 151097-69-7 (2E)-3-(1-benzylpiperidin-4-yl)prop-2-enenitrile 
• 1187595-85-2 2-[1-(ethanesulfonyl)azetidin-3-ylidene]acetonitrile 
• 1616558-97-4 C₂₃H₂₉N₃ 
• 1418143-24-4 2-(4-((3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexylidene)acetonitrile 
• 1153949-11-1 3-(cyanomethylene)azetidine-1-carboxylic acid tert-butyl ester 
• 1205682-76-3 (E)-N-(8-(4-(2-cyanovinyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide 

Relevant articles and documents

Synthesis method of diethyl cyanomethylphosphonate

The invention discloses a synthesis method of diethyl cyanomethylphosphonate. The synthesis method comprises the following steps: carrying out an esterification reaction on chloroacetic acid and ethanol to obtain ethyl chloroacetate; reacting the ethyl chloroacetate with ammonia water to generate chloroacetamide; adding phosphorus pentoxide into the chloroacetamide, performing heating dehydration,distilling out chloroacetonitrile while heating, and finally performing reduced pressure distillation to enable the chloroacetonitrile to be completely distilled out; transferring the chloroacetonitrile into a synthesis reaction kettle, adding a catalyst tetrabutylammonium iodide, heating, dropwise adding triethyl phosphite, and controlling the internal temperature for a reaction to obtain a crude product; and transferring the crude product into a high-purity rectifying tower, and performing purification to respectively rectify triethyl phosphite and diethyl cyanomethylphosphonate.