5059-36-9 Usage
General Description
1-[2-(2,5-DIMETHYL-1H-PYRROL-1-YL)ETHYL]PIPERAZINE is a chemical compound that belongs to the class of piperazines. It has a molecular formula C14H24N2 and a molecular weight of 220.35 g/mol. 1-[2-(2,5-DIMETHYL-1H-PYRROL-1-YL)ETHYL]PIPERAZINE is composed of a piperazine ring with a 2-(2,5-dimethyl-1H-pyrrol-1-yl)ethyl group attached to it. It may have potential pharmaceutical applications due to its structural features and ability to interact with biological systems. Additionally, it is important to handle this compound with caution and follow safety guidelines, as it may have potential hazards if not handled properly. Overall, 1-[2-(2,5-DIMETHYL-1H-PYRROL-1-YL)ETHYL]PIPERAZINE is a chemically interesting compound with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 5059-36-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,5 and 9 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5059-36:
(6*5)+(5*0)+(4*5)+(3*9)+(2*3)+(1*6)=89
89 % 10 = 9
So 5059-36-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H21N3/c1-11-3-4-12(2)15(11)10-9-14-7-5-13-6-8-14/h3-4,13H,5-10H2,1-2H3/p+2
5059-36-9Relevant articles and documents
Discovery and optimisation studies of antimalarial phenotypic hits
Mital, Alka,Murugesan, Dinakaran,Kaiser, Marcel,Yeates, Clive,Gilbert, Ian H.
supporting information, p. 530 - 538 (2015/10/12)
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were identified. Characterization of these compounds is discussed, along with approaches to optimise the physicochemical properties. The in vitro antimalarial activity of these compounds against P. falciparum K1 had EC50 values in the range of 0.09e29 mM, and generally good selectivity (typically >100-fold) compared to a mammalian cell line (L6). One example showed no significant activity against a rodent model of malaria, and more work is needed to optimise these compounds.
