5059-38-1

Basic information

• Product Name: 1-(2-O,3-O,4-O,6-O-Tetraacetyl-β-D-glucopyranosyl)-1H-indole
• Synonyms: 1-(2-O,3-O,4-O,6-O-Tetraacetyl-β-D-glucopyranosyl)-1H-indole
• CAS NO: 5059-38-1
• Molecular Formula: C₂₂H₂₅NO₉
• Molecular Weight: 447.4352
• Mol File: 5059-38-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-O,3-O,4-O,6-O-Tetraacetyl-β-D-glucopyranosyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-O,3-O,4-O,6-O-Tetraacetyl-β-D-glucopyranosyl)-1H-indole(5059-38-1)
• EPA Substance Registry System: 1-(2-O,3-O,4-O,6-O-Tetraacetyl-β-D-glucopyranosyl)-1H-indole(5059-38-1)

Safety Data

• Hazardous Substances Data: 5059-38-1(Hazardous Substances Data)

Upstream product

• 22855-03-4 1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)indoline 
• 496-15-1 1-indoline 
• 39264-64-7 1-(β-D-glucopyranosyl)indoline 
• 50-99-7 D-glucose 
• 604-69-3 β-D-glucose pentaacetate 
• 2280-44-6 D-Glucose 
• 23477-48-7 1-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)indoline 
• 4163-60-4 β-D-galactose peracetate 
• 10257-28-0 D-Galactose 
• 5059-37-0 β-N-D-Galactopyranosyl-indol 
• 108-24-7 acetic anhydride 
• 39264-63-6 1-(β-D-galactopyranosyl)indoline 

Downstream Products

• 1404307-38-5 C₃₁H₃₃NO₁₀ 
• 1493759-80-0 3-(4-cyclopentylphenylmethyl)-1-(β-D-glucopyranosyl)indole 
• 1493759-35-5 C₃₂H₃₅NO₉ 
• 1493759-38-8 C₃₃H₃₇NO₉ 
• 1493759-41-3 C₃₄H₃₉NO₉ 
• 1452838-63-9 3-(4-cyclopropylphenylmethyl)-1-(β-D-glucopyranosyl)indole 
• 1493759-79-7 3-(4-cyclobutylphenylmethyl)-1-(β-D-glucopyranosyl)indole 
• 1493759-13-9 C₃₄H₃₇NO₁₀ 

Relevant articles and documents

Catalytic Aerobic Dehydrogenatin of N-Heterocycles by N-Hydoxyphthalimide

Catalytic methods for the aerobic dehydrogenation of N-heterocycles are reported. In most cases, indoles are accessed efficiently from indolines using catalytic N-hydroxyphthalimide (NHPI) as the sole additive under air. Further studies revealed an improved catalytic system of NHPI and copper for the preparation of other heteroaromatics, for example quinolines. (Figure presented.).

Synthesis of 1,3- and 2,3-diglycosylated indoles as potential trisaccharide mimetics

Diglycosylated heteroaromatics may serve as metabolically stable mimetics of trisaccharides. Herein, the preparation of several 1,3- and 2,3-diglycosylindoles by direct C-glycosylation of monoglycosylated precursors is described. Georg Thieme Verlag Stuttgart ? New York.

1-( -D-GLYCOPYRANOSYL)-3-SUBSTITUTED NITROGENOUS HETEROCYCLIC COMPOUND, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE THEREOF

A compound having SGLT1 and/or SGLT2 inhibitory activity which is usable as an agent for the prevention or treatment of diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications, obesity, etc. It is a 1-(β-D-glycopyranosyl)-3-substituted nitrogen-containing heterocyclic compound represented by the general formula (I), a prodrug, or a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof; an SGLT inhibitor containing the same; a pharmaceutical composition containing the same and a medicinal use thereof. In the formula, ring A represents optionally substituted aryl or heteroaryl; Q1 to Q5 independently represent a carbon atom having a hydrogen atom or substituent bonded thereto or a nitrogen atom; E represents a single bond, alkylene, -O-, -S- or -NH-; and R.represents methyl, ethyl, fluoromethyl or hydroxymethyl.