5062-75-9

Basic information

• Product Name: Cyclopentanemethylamine, 1-(dimethylamino)-N,N-dimethyl- (7CI,8CI)
• Synonyms: Cyclopentanemethylamine, 1-(dimethylamino)-N,N-dimethyl- (7CI,8CI)
• CAS NO: 5062-75-9
• Molecular Formula: C10H22N2
• Molecular Weight: 170.29508
• Product Categories: CYCLOPENTANE
• Mol File: 5062-75-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopentanemethylamine, 1-(dimethylamino)-N,N-dimethyl- (7CI,8CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanemethylamine, 1-(dimethylamino)-N,N-dimethyl- (7CI,8CI)(5062-75-9)
• EPA Substance Registry System: Cyclopentanemethylamine, 1-(dimethylamino)-N,N-dimethyl- (7CI,8CI)(5062-75-9)

Safety Data

• Hazardous Substances Data: 5062-75-9(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 5062-66-8 1-(aminomethyl)cyclopentanamine 

Relevant articles and documents

Bulky Diamine Ligand Promotes Cross-Coupling of Difluoroalkyl Bromides by Iron Catalysis

Although iron-catalyzed cross-coupling of Grignard reagents with alkyl halides has been well established, the adoption of the reaction for fluoroalkylations has not been reported because traditional catalytic systems often lead to defluorination reactions. Described herein is the investigation of an iron-catalyzed cross-coupling between arylmagnesium bromides and difluoroalkyl bromides with modified N,N,N′,N′-tetramethyl-ethane-1,2-diamine (TMEDA) as a ligand. The use of this bulky diamine, in which a butylene is substituted at one carbon atom of the ethylene backbone in TMEDA, enables the iron-catalyzed difluoroalkylation under mild reaction conditions with a wide range of difluoroalkyl bromides, including vulnerable bromodifluoromethane, thus providing a general and cost-efficient route for applications in medicinal chemistry.