507-55-1

Basic information

• Product Name: 1,3-DICHLORO-1,1,2,2,3-PENTAFLUOROPROPANE
• Synonyms: HCFC-225CB;1,3-DICHLORO-1,1,2,2,3-PENTAFLUOROPROPANE;1,3-Dichlor-1,1,2,2,3-pentafluorpropan;1,3-dichloro-1,1,2,2,3-pentafluoro-propan;1,3-dichloro-1,2,2,3,3-pentafluoro-propane;hcfc225bc;H-FCKW-225cb;Propane,1,3-dichloro-1,1,2,2,3-pentafluoro-
• CAS NO: 507-55-1
• Molecular Formula: C₃HCl₂F₅
• Molecular Weight: 202.94
• EINECS: 208-076-9
• Product Categories: refrigerants
• Mol File: 507-55-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: -96.9°C
• Boiling Point: 56°C
• Flash Point: °C
• Appearance: /
• Density: 1,56 g/cm3
• Refractive Index: 1.326
• CAS DataBase Reference: 1,3-DICHLORO-1,1,2,2,3-PENTAFLUOROPROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DICHLORO-1,1,2,2,3-PENTAFLUOROPROPANE(507-55-1)
• EPA Substance Registry System: 1,3-DICHLORO-1,1,2,2,3-PENTAFLUOROPROPANE(507-55-1)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-59
• Safety Statements: 23-36/37/39
• RIDADR: 3082
• Hazardous Substances Data: 507-55-1(Hazardous Substances Data)

Usage

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

1,3-DICHLORO-1,1,2,2,3-PENTAFLUOROPROPANE is chemically inert in many situations, but can react violently with strong reducing agents such as the very active metals and the active metals. They suffer oxidation with strong oxidizing agents and under extremes of temperature. Strong bases may release toxic gases.

InChI:InChI=1/C3HCl2F5/c4-1(6)2(7,8)3(5,9)10/h1H

Synthetic route

1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) → 3-chloro-1,1,1,2,2,3-hexafluoropropane (422-57-1) + 1-chloro-1,1,2,2,3,3-hexafluoropropane (422-55-9) + 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1)

Conditions	Yield
With hydrogen fluoride; chromium(III) oxide at 280℃;	A 3% B 16% C 5% D 44%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 2,3-dichloro-1,1,2,3,3-pentafluoropropane (422-44-6) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 2.3% B 12.4% C 30.5% D 12.5%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,2,2-trichloro-1,1,3,3-tetrafluoropropane (422-32-2) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 0.5% B 12.4% C 30.5% D 12.5%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 0.6% B 12.4% C 30.5% D 12.5%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-1,2,2,3-tetrafluoropropane (422-53-7) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 8.9% C 30.5% D 12.5%
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 8.9% C 30.5% D 0.5%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + 2,2-dichloro-1,1,1,3,3-pentafluoropropane (128903-21-9)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 30.5% C 12.5% D 2.4%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + 2,2,3-trichloro-1,1,1,3-tetrafluoropropane (139754-75-9)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 30.5% C 12.5% D 4.4%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + 1,1-dichloro-1,2,2,3,3-pentafluoropropane (13474-88-9)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 30.5% C 12.5% D 1.5%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + (2RS,3SR)-2,3-dichloro-1,1,1,2,3-pentafluoropropane (422-48-0, 111512-51-7, 111512-55-1)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 30.5% C 12.5% D 6.6%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + (2RS,3RS)-2,3-dichloro-1,1,1,2,3-pentafluoropropane (422-48-0, 111512-51-7, 111512-55-1)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 30.5% C 12.5% D 6.9%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + (2SR,3SR)-1,2,3-trichloro-1,1,2,3-tetrafluoropropane (422-42-4, 144909-55-7, 144909-56-8)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 30.5% C 12.5% D 6.3%

Chlorodifluoromethane (75-45-6) + Chlorotrifluoroethylene (79-38-9) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 1,1,3-trichloro-2,2,3,3-tetrafluoropropane (422-54-8) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + (2SR,3RS)-1,2,3-trichloro-1,1,2,3-tetrafluoropropane (422-42-4, 144909-55-7, 144909-56-8)

Conditions	Yield
With aluminium trichloride at 0 - 10℃; for 10h; Further byproducts given;	A 12.4% B 30.5% C 12.5% D 3.6%

polytetrafluoroethylene (116-14-3) + Dichlorofluoromethane (75-43-4) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1)

Conditions	Yield
With aluminium trichloride at 50 - 125℃;
With aluminium trichloride at 50 - 125℃;

polytetrafluoroethylene (116-14-3) + aluminium trichloride (7446-70-0) + Dichlorofluoromethane (75-43-4) → 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1)

Conditions	Yield
at 50 - 125℃; reagiert analog mit Trifluorchloraethylen und mit Tetrachloraethylen;
at 50 - 125℃;
at 50 - 125℃;

4-(2-hydroxyethyl)-2,2-dimethyl-1,3-dioxolane (5754-34-7) + 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + perfluoro-2,5-dimethyl-3,6-dioxanonanoyl fluoride (2641-34-1) → C16H13O6F17

Conditions	Yield
With sodium fluoride at 20℃; for 20h;	67%

3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 1,1,1,2-tetrafluoropropane (421-48-7) + 1,1,1,2,2-pentafluoropropane (1814-88-6)

Conditions	Yield
With hydrogen; potassium acetate; palladium 10% on activated carbon In ethanol at 65℃; under 7757.43 Torr; for 16h; Product distribution / selectivity;

3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 2,3,3,3-tetrafluoro-propene (754-12-1) + 1,1,1,2-tetrafluoropropane (421-48-7) + 1,1,1,2,2-pentafluoropropane (1814-88-6)

Conditions	Yield
With hydrogen; potassium acetate; palladium 10% on activated carbon In ethanol at 120℃; under 7757.43 Torr; for 16h; Product distribution / selectivity;

3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 3-chloro-1,1,1,2,2-pentafluoropropane (422-02-6) + 2,3,3,3-tetrafluoro-propene (754-12-1)

Conditions	Yield
With hydrogen; potassium acetate; palladium 10% on activated carbon In ethanol at 40 - 45℃; under 7757.43 Torr; for 16h; Product distribution / selectivity;

3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 3-chloro-1,1,1,2,2-pentafluoropropane (422-02-6) + 1,1,1,2,2-pentafluoropropane (1814-88-6)

Conditions	Yield
With ammonium formate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 98 - 100℃; under 10343.2 Torr; for 22h; Product distribution / selectivity;
With hydrogen; 1% Pd/C at 80 - 145℃; under 760.051 - 1520.1 Torr; Product distribution / selectivity; Gas phase;

3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 1,1-dichloro-1,2,2,3,3-pentafluoropropane (13474-88-9)

Conditions	Yield
With SbCl5; SbF3 In chloroform

3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 3-chloro-1,1,1,2,2-pentafluoropropane (422-02-6) + 1,1,1-trifluoropropane (421-07-8) + 2,3,3,3-tetrafluoro-propene (754-12-1) + 1,1,1,2-tetrafluoropropane (421-48-7) + 1-chloro-1,1,2,2,3-pentafluoropropane (677-55-4) + 1,1,1,2,2-pentafluoropropane (1814-88-6) + 1,1,2,2,3-pentafluoropropane (679-86-7) + 1-chloro-1,2,2,3,3-pentafluoropropane (679-99-2)

Conditions	Yield
With hydrogen; fluorided Pd/Al2O3 at 300 - 350℃; Product distribution / selectivity;

...Expand

1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 2,2-dichloro-1,1,1,3,3-pentafluoropropane (128903-21-9)

Conditions	Yield
aluminum (III) chloride; trichlorofluoromethane at 0 - 50℃; Product distribution / selectivity;

1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 1-chloro-1,1,2,2,3,3-hexafluoropropane (422-55-9) + 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9) + 2,2-dichloro-1,1,1,3,3-pentafluoropropane (128903-21-9)

Conditions	Yield
partially fluorinated aluminum oxide at 300℃; for 10.0056h; Product distribution / selectivity; Inert atmosphere;

1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 2,2-dichloro-1,1,1,3,3-pentafluoropropane (128903-21-9) → 1-chloro-1,1,2,2,3,3-hexafluoropropane (422-55-9) + 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0) + 1,1,2-trichloro-2,3,3,3-tetrafluoropropane (422-47-9)

Conditions	Yield
partially fluorinated aluminum oxide at 300℃; for 10.0056h; Inert atmosphere;

1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) + 2,2-dichloro-1,1,1,3,3-pentafluoropropane (128903-21-9) → 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0)

Conditions	Yield
partially fluorinated aluminum oxide at 230℃; for 10.0056h; Product distribution / selectivity; Inert atmosphere;

1,3-dichloro-1,1,2,2,3-pentafluoropropane (507-55-1) → 3,3-dichloro-1,1,1,2,2-pentafluoropropane (422-56-0)

Conditions	Yield
With aluminum oxide at 250 - 400℃; for 4h; Reagent/catalyst; Inert atmosphere;

Upstream product

• 116-14-3 polytetrafluoroethylene 
• 75-43-4 Dichlorofluoromethane 
• 422-54-8 1,1,3-trichloro-2,2,3,3-tetrafluoropropane 
• 7446-70-0 aluminium trichloride 
• 75-45-6 Chlorodifluoromethane 
• 79-38-9 Chlorotrifluoroethylene 

Downstream Products

• 422-56-0 3,3-dichloro-1,1,1,2,2-pentafluoropropane 
• 128903-21-9 2,2-dichloro-1,1,1,3,3-pentafluoropropane 
• 422-02-6 3-chloro-1,1,1,2,2-pentafluoropropane 
• 421-07-8 1,1,1-trifluoropropane 
• 754-12-1 2,3,3,3-tetrafluoro-propene 
• 421-48-7 1,1,1,2-tetrafluoropropane 
• 677-55-4 1-chloro-1,1,2,2,3-pentafluoropropane 
• 1814-88-6 1,1,1,2,2-pentafluoropropane 
• 679-86-7 1,1,2,2,3-pentafluoropropane 
• 679-99-2 1-chloro-1,2,2,3,3-pentafluoropropane 
• 13474-88-9 1,1-dichloro-1,2,2,3,3-pentafluoropropane 
• 422-55-9 1-chloro-1,1,2,2,3,3-hexafluoropropane 
• 422-47-9 2,3,3-trichloro-1,1,1,2-tetrafluoropropane 

Relevant articles and documents

19F nuclear magnetic resonance studies of halogenated propanes

The relationship between 19F chemical shifts in halogenated propanes and their structures are elucidated using MNDO calculations to determine the population of rotamers.The pairs of atom gauche to a fluorine atom and van der Waals interaction between the two terminal substituents are responsible for the 19F chemical shifts.The differences among chemical shifts in diastereomers are also discussed in terms of the conformation of molecule.