508193-99-5

Basic information

• Product Name: benzylamino-pyridin-4-yl-acetic acid methyl ester
• Synonyms: benzylamino-pyridin-4-yl-acetic acid methyl ester
• CAS NO: 508193-99-5
• Molecular Weight: 256.304
• Mol File: 508193-99-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzylamino-pyridin-4-yl-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: benzylamino-pyridin-4-yl-acetic acid methyl ester(508193-99-5)
• EPA Substance Registry System: benzylamino-pyridin-4-yl-acetic acid methyl ester(508193-99-5)

Safety Data

• Hazardous Substances Data: 508193-99-5(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 67-56-1 methanol 
• 72954-83-7 N-<(pyridin-4-yl)methylidene>benzylamine 

Relevant articles and documents

A highly efficient, asymmetric synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase

(Chemical Equation Presented) An efficient two-pot, asymmetric synthesis of benzothiadiazine-substituted tetramic acids is reported. Starting from commercially available α-amino acids or esters, reductive amination followed by a novel one-pot amide bond formation/Dieckmann cyclization provided the desired products in high yield and optical purity. An analogous solid-phase approach to the same targets is also presented. These compounds were found to be potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase.