50868-51-4

Basic information

• Product Name: stigmasta-4,22-diene-3,6-dione
• CAS NO: 50868-51-4
• Molecular Weight: 424.667
• Mol File: 50868-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: stigmasta-4,22-diene-3,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: stigmasta-4,22-diene-3,6-dione(50868-51-4)
• EPA Substance Registry System: stigmasta-4,22-diene-3,6-dione(50868-51-4)

Safety Data

• Hazardous Substances Data: 50868-51-4(Hazardous Substances Data)

Upstream product

• 83-48-7 Stigmasterol 

Downstream Products

• 36450-01-8 6β-hydroxystigmasta-4,22-dien-3-one 
• 167958-89-6 stigmasta-4,22-diene-3β,6β-diol 

Relevant articles and documents

Stereospecific oxidation of 3β-hydroxysteroids by persolvent fermentation with Pseudomonas sp. ST-200

Pseudomonas sp. strain ST-200 isolated from a humus soil effectively oxidizes cholesterol dissolved in organic solvents but not that suspended in the growth medium. The organism does not assimilate cholesterol. This organism oxidized a variety of 5α- or 5-ene-steroids dissolved in organic solvent. First, the 3β-OH group was oxidized to a ketone group. The 3α-OH group was scarcely oxidized. Successively, C-6 position of 5-ene-steroids was hydroxylated, and a double bond of 5-ene-steroids was transferred from Δ5 to Δ4. Then, the 6-OH group was oxidized to a ketone group. Persolvent fermentation with ST-200 would provide an effective, convenient, and stereospecific method to oxidize the C-3 and C-6 positions of steroids.