5089-33-8

Basic information

• Product Name: 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE
• Synonyms: P-BROMO-N,N-BIS TRIMETHYL SILYL ANILINE;4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE;N,N-Bis(trimethylsilyl)-4-bromoaniline;N-(4-broMophenyl)-1,1,1-triMethyl-N-(triMethylsilyl)silanaMine;4-Bromo-N,N-bis(trimethylsilyl)aniline 97%;Silanamine, N-(4-bromophenyl)-1,1,1-trimethyl-N-(trimethylsilyl)-;-1,1,1-trimethyl-N-(trimethylsilyl);EOS-60917
• CAS NO: 5089-33-8
• Molecular Formula: C₁₂H₂₂BrNSi₂
• Molecular Weight: 316.38
• Product Categories: Nitrogen Compounds;Organic Building Blocks;Protected Amines
• Mol File: 5089-33-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 156-158 °C23 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.121 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00127mmHg at 25°C
• Refractive Index: 1.511
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.54±0.50(Predicted)
• CAS DataBase Reference: 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE(5089-33-8)
• EPA Substance Registry System: 4-BROMO-N,N-BIS(TRIMETHYLSILYL)ANILINE(5089-33-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: No
• Hazardous Substances Data: 5089-33-8(Hazardous Substances Data)

Usage

Uses

4-Bromo-N,N-bis(trimethylsilyl)aniline is an N-protected aryl reagent used in the synthesis of:Hydrophilic conjugated porphyrin dimers for one-photon and two-photon photodynamic therapy.Functionalized organometallic polymer, poly(ferrocenylsilane).Borylanilines such as 4-(dimesitylboryl)aniline and 4-(dimesitylboryl)-3,5-dimethylaniline.Silicon-containing oligomeric poly(imido-amides) (PIAs).

InChI:InChI=1/C12H22BrNSi2/c1-15(2,3)14(16(4,5)6)12-9-7-11(13)8-10-12/h7-10H,1-6H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 106-40-1 4-bromo-aniline 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 63911-87-5 N-(trimethylsilyl)-4-bromoaniline 
• 996-50-9 N,N-diethyl-1,1,1-trimethylsilanamine 

Downstream Products

• 2997-53-7 4-aminophenyl diphenyl methanol 
• 57049-35-1 4,4'-Diaminotriphenylmethanol 
• 102368-04-7 4-methylphenylsilyl chloride 
• 244206-51-7 3,20-bis-ethylenedioxy-5α,17α-dihydroxy-11β-(4-aminophenyl)-19-norpregn-9-ene 
• 440333-21-1 4-[bis(trimethylsilyl)amino]phenyl diphenyl methanol 
• 106-40-1 4-bromo-aniline 
• 16054-48-1 (Z)-2-(4-bromophenyl)-1-phenyldiazene 1-oxide 
• 20972-43-4 trans-azoxybenzene 
• 6141-96-4 (E)-1-(4-bromophenyl)-2-phenyldiazene 
• 321596-88-7 4-(3-TRIFLUOROMETHYLBENZYL)ANILINE 
• 507229-24-5 C₅H₅FeC₅H₄BBrNSi(CH₃)3C₆H₄Br 
• 507229-50-7 C₅H₄BBr₂FeC₅H₄BBrNSi(CH₃)3BrC₆H₄ 
• 507229-55-2 Fe(C₅H₄BBrNSi(CH₃)3BrC₆H₄)2 
• 1062503-71-2 Zn((MeO(CH₂CH₂O)3C₆H₄)2(H₂NC₆H₄)C₂₀H₉N₂) 

Relevant articles and documents

Synthesis and Characterization of (Disilylanilino)Phosphines

(Graphical Abstract) The disilyl(4-bromo)aniline (Me3Si)2NC6H4Br (A) readily undergoes metal-halogen exchange to give the reactive organolithium derivative (Me3Si)2NC6H4/su

POLYAMIC ACID PRECURSOR COMPOUND INCLUDING SILICON, POLYAMIC ACID AND ORGANIC INORGANIC HYBRID POLYIMIDE FILM

Provided is a polyamic acid precursor compound including silicon, which is represented by chemical formula 1. In chemical formula 1, X and R_1 are the same as defined in the specification. One embodiment of the present invention provides the polyamic acid precursor compound including silicon, which is excellent in light transmittance and can be induced to a polyamic acid having excellent heat resistance and high temperature durability.COPYRIGHT KIPO 2018

Synthesis of potential antitubercular and antimicrobial s-triazine-based scaffolds via Suzuki cross-coupling reaction

Two series of bis(3,5-dimethylpiperidinyl)-1,3,5-triazinyl)-N-(phenyl/ benzothiazolyl)-acetamides were synthesized so as to investigate their antimicrobial and antimycobacterial actions. Intermediate 4-(4,6-bis(3,5- dimethylpiperidin-1-yl)-1,3,5-triazin-2-yl)aniline was synthesized by palladium-catalyzed Suzuki cross-coupling reaction to furnish C-C bond formation to s-triazine ring. Pharmacological screening against eight bacteria (S. aureus, B. cereus, E. coli, P. aeruginosa, K. pneumoniae, S. typhi, P. vulgaris, and S. flexneri), four fungi (A. niger, A. fumigatus, A. clavatus, and C. albicans), and Mycobacterium tuberculosis H37Rv was examined and the effects of various substituents on biological profiles (MIC, 1.56-50 μg/mL) of final analogues were investigated. Four (8c, 8i, 9d, 9j) of the final analogues displayed antimycobacterial activity (3.12-6.25 μg/mL) equipotent to standard drugs.