50907-31-8

Basic information

• Product Name: 5-(2,6-DICHLOROPHENYL)-1H-TETRAZOLE
• Synonyms: 5-(2,6-DICHLOROPHENYL)-1H-TETRAZOLE
• CAS NO: 50907-31-8
• Molecular Formula: C₇H₄Cl₂N₄
• Molecular Weight: 215.04
• EINECS: -0
• Mol File: 50907-31-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 202-204°C
• Boiling Point: 399.9 °C at 760 mmHg
• Flash Point: 227.9 °C
• Appearance: /
• Density: 1.574 g/cm³
• Vapor Pressure: 1.32E-06mmHg at 25°C
• Refractive Index: 1.641
• PKA: 3.27±0.10(Predicted)
• BRN: 5268246
• CAS DataBase Reference: 5-(2,6-DICHLOROPHENYL)-1H-TETRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2,6-DICHLOROPHENYL)-1H-TETRAZOLE(50907-31-8)
• EPA Substance Registry System: 5-(2,6-DICHLOROPHENYL)-1H-TETRAZOLE(50907-31-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-36/37/39-27
• HazardClass: IRRITANT
• Hazardous Substances Data: 50907-31-8(Hazardous Substances Data)

Usage

Chemical Properties

white solid

InChI:InChI=1/C7H4Cl2N4/c8-4-2-1-3-5(9)6(4)7-10-12-13-11-7/h1-3H,(H,10,11,12,13)

Upstream product

• 1194-65-6 2,6-dichloro-benzonitrile 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 25185-95-9 2,6-dichlorobenzaldoxime 

Downstream Products

• 117594-40-8 N-[1-[5-(2,6-Dichloro-phenyl)-tetrazol-2-yl]-1-phenyl-meth-(Z)-ylidene]-N'-(4-nitro-phenyl)-hydrazine 
• 117594-29-3 N-[1-[5-(2,6-Dichloro-phenyl)-tetrazol-1-yl]-1-phenyl-meth-(Z)-ylidene]-N'-(4-nitro-phenyl)-hydrazine 
• 117594-52-2 [3-(2,6-Dichloro-phenyl)-5-phenyl-[1,2,4]triazol-4-yl]-(4-nitro-phenyl)-amine 
• 77455-47-1 5-(2,6-dichlorophenyl)-2-methyltetrazole 
• 77455-48-2 5-(2,6-dichlorophenyl)-1-methyltetrazole 

Relevant articles and documents

A comparative study between heterogeneous stannous chloride loaded silica nanoparticles and a homogeneous stannous chloride catalyst in the synthesis of 5-substituted 1: H -tetrazole

Heterogeneous SnCl2-nano-SiO2 efficiently catalyzed 5-substituted 1H-tetrazole synthesis with excellent yield. The catalyst was characterized by using FT-IR, TGA, TEM, and EDX. It is widely applicable on aliphatic, aromatic, heteroaromatic and sterically hindered nitriles with five time recyclability. Being simple and an economically viable approach for the synthesis of SnCl2-nano-SiO2 are additional advantages.

Synthetic application of gold nanoparticles and auric chloride for the synthesis of 5-substituted 1H-tetrazoles

An effective one-pot, convenient gold catalyzed synthesis of 5-substituted 1H-tetrazoles has been discussed. The study demonstrated the comparative overview for utilization of gold(iii) and gold nano-particles (spheres) as a catalyst. Detailed understandi

Design and synthesis of low molecular weight compounds with complement inhibition activity

An attempt was made to synthesize a series of non-cytotoxic low molecular weight compounds of varying substitutions and functionalities having pharmacophore activity like carbonyl compounds, carboxylic acid and bioisosteres like tetrazole and phenyl acrylic acid. The in vitro assay of these analogues for the inhibition of complement activity revealed significant inhibitory activity for varying substituents and, particularly, for bioisosteres, that is, tetrazole and phenyl acrylic acid derivatives.