5092-01-3Relevant articles and documents
Preparation method of 18 beta-methyl glycyrrhetinate
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Paragraph 0024; 0030-0063, (2021/11/27)
The invention provides a preparation method of 18 beta-methyl glycyrrhetinate, which comprises the following steps: taking 18 beta-glycyrrhetinic acid and trimethylsilyl diazomethane as raw materials, and reacting to prepare the 18 beta-methyl glycyrrhetinate. According to the invention, 18 beta-glycyrrhetinic acid is used as a starting material and is subjected to one-step methyl esterification reaction with trimethylsilyl diazomethane to obtain 18 beta-methyl glycyrrhetinate, the synthesis process is simple, the synthesis process conditions are mild, the yield is up to 99.2% or above, the product quality is good, and the content is greater than 99.5%. Besides, through selection of a plurality of parameters such as the solvent, the reaction time and the material dosage, the yield and the purity of the reaction are further improved, and a basis is provided for industrial production.
Synthesis and inhibition of α-glucosidase of methyl glycyrrhetinate glycosides
Zhang, Wei,Wang, He-Ying,Wang, Huai-Xu,Zhu, Zhen-Yuan
supporting information, p. 1874 - 1880 (2019/07/22)
The synthesis of the methyl glycyrrhetinate glycosides and inhibition of α-glucosidase were studied. The carboxyl group of glycyrrhetinic acid was methylated, and glucose and galactose were introduced into the hydroxyl group to obtain compounds 7 and 12.
Quaternary ammonium glycyrrhetinic acid cationic surfactant as well as preparation method and application thereof (by machine translation)
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Paragraph 0041; 0043; 0044, (2020/05/01)
The invention discloses a quaternary ammonium glycyrrhetinic acid cationic surfactant and a preparation method and application. thereof, and the critical micelle concentration of the surfactant at room temperature is 5 × 10. - 4 mol/L, Can descend the surface tension from 72mN/m to 47mN/m. and, the surfactant has better regulation and control effect on the bouncing behavior of the liquid drop on the hydrophobic solid surface, and the surfactant concentration on the surface of the blade such as dive, PTFE can be 5 × 10 higher. - 4 At mol/L, can obviously inhibit the liquid drop bouncing, and realize better spreading. and, the quaternary ammonium glycyrrhetinic acid cationic surfactant in the invention can extend to various crop blades, such as wheat, rice, corn, cabbage and other blades, have great application prospects, in the field of agricultural industry. (by machine translation)
