50976-96-0Relevant articles and documents
1-(2′-Bromobenzyl)-6,7-dihydroxy- N-methyl-tetrahydroisoquinoline and 1,2-Demethyl-nuciferine as Agonists in Human D2 Dopamine Receptors
Cabedo, Nuria,Cortes, Diego,Loza, Mabel,Marques, Patrice,Moreno, Laura,Silva, Andrea G.,Vila, Laura,Castro, Marián,Sanz, María-Jesús
, (2020/02/04)
Certain D2-like dopamine receptor (DR) agonists are useful therapeutically as antiparkinsonian drugs, whereas D2-like DR antagonists or partial agonists are proven effective as antipsychotics. Two isoquinoline derivatives, 1-(2′-brom
3,4-Dihydroxy- and 3,4-methylenedioxy- phenanthrene-type alkaloids with high selectivity for D2 dopamine receptor
Moreno, Laura,Cabedo, Nuria,Ivorra, Maria Dolores,Sanz, Maria-Jesus,Castel, Arturo Lopez,Carmen Alvarez,Cortes, Diego
, p. 4824 - 4827 (2013/09/02)
Dopamine-mediated neurotransmission plays an important role in relevant psychiatric and neurological disorders. Nowadays, there is an enormous interest in the development of new drugs acting at the dopamine receptors (DR) as potential new targets for the