50996-03-7

Basic information

• Product Name: Benzamide, N-(2-oxopropyl)-
• Synonyms: N-acetonylbenzamide;1-benzoylamino-propan-2-one;benzamidoacetone;1-Benzoylamino-2-propanone;N-benzoylaminoacetic acid
• CAS NO: 50996-03-7
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.203
• Mol File: 50996-03-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(2-oxopropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(2-oxopropyl)-(50996-03-7)
• EPA Substance Registry System: Benzamide, N-(2-oxopropyl)-(50996-03-7)

Safety Data

• Hazardous Substances Data: 50996-03-7(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 78-96-6 3-amino-2-propanol 
• 23054-66-2 N-(2-hydroxypropyl)benzamide 
• 1464-98-8 N-(prop-2-yn-1-yl)benzamide 
• 92959-54-1 N₁-benzoyl-N₂-tert-butoxycarbonyldiazene 
• 92789-04-3 N'-benzoylhydrazinecarboxylic acid tert-butyl ester 
• 495-69-2 Hippuric Acid 
• 532-94-5 sodium hippurate 
• 108-24-7 acetic anhydride 
• 7647-01-0 hydrogenchloride 
• 143287-24-5 4-<(Z)-1-ethoxyethylidene>-2-phenyl-5-oxazolone 
• 10283-95-1 N-allylbenzamide 
• 7737-17-9 1-aminopropan-2-one hydrochloride 
• 57784-67-5 4-<(E)-1-ethoxyethylidene>-2-phenyl-5-oxazolone 

Downstream Products

• 13040-58-9 7-methylpterin 
• 4215-07-0 7-methyl-2,4-diaminopteridine 
• 5221-67-0 5-methyl-2-phenyloxazole 
• 5221-69-2 5-methyl-2-phenylthiazole 
• 501031-13-6 N-[1-acetyl-4-(trimethylsilyl)but-3-ynyl]benzamide 
• 30057-79-5 N-(1-acetylbut-3-enyl)benzamide 

Relevant articles and documents

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Synthesis of α-aminocarbonyl compounds via hetero dielsalder reaction

A synthetic route to α-aminoketone derivatives via a hetero DielsAlder reaction is described. Diacylhydrazine was oxidized by tert-butyl hypochlorite in the presence of pyridine. After evaporation, the hetero DielsAlder reaction with diene was carried out without isolation of the azodicarbonyl compound. Quantitative hetero DielsAlder reaction was possible with 1 equivalent of diene when Hf(OTf)4 or AgOTf was used as the catalyst. The NN bond of the product was cleaved by SmI2-reduction in the presence of tert-BuOH in THF. Further, ozonolysis of the C=C double bond afforded the α-aminoketone derivative in excellent yield.

Characterization of vinylgold intermediates: Gold-mediated cyclization of acetylenic amides

Hidden nuggets of gold: Mono- and divinylgold complexes (see scheme), key intermediates in the gold-mediated cyclization reaction of N-(propargyl) benzamides, are characterized by NMR and X-ray diffraction analyses. The monovinylgold intermediates undergo

Antidiabetic agents

The present invention provides compounds of Formula (I): wherein A, X, Q, Y, B, D, Z, and E have any of the values defined in the specification, and pharmaceutically acceptable salt thereof, that are useful as antidiabetic agents. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula I, processes for preparing compounds of Formula I, and intermediates useful for preparing compounds of Formula I.