5100-98-1

Basic information

• Product Name: 3-CHLORO-2-IODOTOLUENE
• Synonyms: BUTTPARK 121\11-21;3-CHLORO-2-IODOTOLUENE;3-Chloro-2-iodotoluene,98%;1-chloro-2-iodo-3-methylbenzene
• CAS NO: 5100-98-1
• Molecular Formula: C₇H₆ClI
• Molecular Weight: 252.48
• EINECS: -0
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Halogen toluene;Chlorine Compounds;Iodine Compounds
• Mol File: 5100-98-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 25-27°C
• Boiling Point: 134-136°C 20mm
• Flash Point: 134-136°C/20mm
• Appearance: /
• Density: 1.806
• Vapor Pressure: 0.0331mmHg at 25°C
• Refractive Index: 1.6080
• Storage Temp.: 2-8°C(protect from light)
• Sensitive: Light Sensitive
• BRN: 2961541
• CAS DataBase Reference: 3-CHLORO-2-IODOTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-2-IODOTOLUENE(5100-98-1)
• EPA Substance Registry System: 3-CHLORO-2-IODOTOLUENE(5100-98-1)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36/38-50/53-41-37/38
• Safety Statements: 26-36/37/39-61-60-39
• Hazardous Substances Data: 5100-98-1(Hazardous Substances Data)

Usage

General Description

3-Chloro-2-iodotoluene is an organic chemical compound with the molecular formula C7H6ClI. It belongs to the class of halogenated toluenes, which are commonly used as intermediates in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 3-Chloro-2-iodotoluene is a colorless to pale yellow liquid with a pungent odor, and it is primarily used in the production of dyes, pigments, and other fine chemicals. It is also a key building block in the synthesis of organic compounds, serving as a versatile substrate for various chemical transformations, such as halogenation, nitration, and Friedel-Crafts reactions. Due to its reactivity and utility in organic synthesis, 3-Chloro-2-iodotoluene is commonly utilized by researchers and chemists in the laboratory setting.

InChI:InChI=1/C7H6ClI/c1-5-3-2-4-6(8)7(5)9/h2-4H,1H3

Upstream product

• 6277-17-4 2-iodo-3-nitrotoluene 
• 87-63-8 2-chloro-6-methylaniline 
• 89938-16-9 2-iodo-1-methyl-3-methylaniline 

Downstream Products

• 19027-68-0 5-methyl-1,2,3,4-tetraphenylnaphthalene 
• 6575-09-3 2-chloro-6-methyl-benzonitrile 
• 1076192-10-3 methyl [2-(bromomethyl)-6-chlorophenyl]acetate 
• 1076192-08-9 methyl (2-chloro-6-methylphenyl)acetate 
• 21327-86-6 2-chloro-6-methylbenzoic acid 
• 108-41-8 1-chloro-3-methylbenzene 

Relevant articles and documents

Method for preparing polysoproxil intermediate

The method comprises the following steps: (1). A hydrogen chloride salt of 2 - chlorine -6 - methylaniline compound 1 is prepared by taking 2 - chlorine -6 - methylaniline compound 1 as a raw material in a suitable solvent, and then subjected to diazotization reaction with a nitration reagent aqueous solution to obtain the diazonium salt 2 - chloro -6 - methylaniline. The iodine-containing reagent is reacted with an iodo reagent to obtain 3 -chloro -2 -iodotoluene compound 2. (2), the compound 2 is reacted with the reactant cyanide to give 2 -chloro -6 -iodo-benzonitrile compound 3. (3), the compound 3 undergoes a hydrolysis reaction to obtain 2 - chloro -6 - methyl benzoic acid compound 4, and the reaction equation is as follows. The method has the advantages of cheap and easily available raw materials, high reaction conversion rate, simplicity and rapidness, mild and controllable reaction conditions, mild reaction conditions, high yield of the obtained product, easy separation and purification, high purity and easy industrial mass production.

VINYLSILYL GRIGNARD REAGENTS AS ARYNE TRAPS. A NEW ROUTE TO (ARYLALKENYL)SILANES.

A general method for preparing (arylalkenyl)silanes via nucleophilic capture of arynes with vinyltrimethylsilyl Grignard reagents is decribed.

Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase

Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase using 7 and/or 8 substituted 1,2,3,4-tetrahydroisoquinoline compounds.