51123-59-2

Basic information

• Product Name: 2-AMINO-6-CHLORO-3-NITROTOLUENE
• Synonyms: 2-AMINO-6-CHLORO-3-NITROTOLUENE;3-Chloro-2-Methyl-6-nitroaniline;3-chloro-2-methyl-6-nitrobenzenamine
• CAS NO: 51123-59-2
• Molecular Formula: C₇H₇ClN₂O₂
• Molecular Weight: 186.59568
• Mol File: 51123-59-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 337.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.415±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -1.66±0.25(Predicted)
• CAS DataBase Reference: 2-AMINO-6-CHLORO-3-NITROTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-6-CHLORO-3-NITROTOLUENE(51123-59-2)
• EPA Substance Registry System: 2-AMINO-6-CHLORO-3-NITROTOLUENE(51123-59-2)

Safety Data

• Hazardous Substances Data: 51123-59-2(Hazardous Substances Data)

Usage

General Description

2-AMINO-6-CHLORO-3-NITROTOLUENE is a chemical compound with the molecular formula C7H7ClN2O2. It is a derivative of toluene, with an amino group at the 2-position, a chlorine atom at the 6-position, and a nitro group at the 3-position. 2-AMINO-6-CHLORO-3-NITROTOLUENE is used in the synthesis of various dyes and pigments, as well as in the production of pharmaceuticals and agrochemicals. It is important to handle this chemical with care, as it is considered hazardous due to its potential toxic and environmental effects.

Upstream product

• 51123-58-1 acetic acid-(3-chloro-2-methyl-6-nitro-anilide) 
• 87-60-5 3-chloro-2-methylbenzenamine 
• 83-42-1 6-chloro-2-nitrotoluene 
• 7463-35-6 N-(3-chloro-2-methylphenyl)acetamide 
• 290353-56-9 6-chloro-2,3-dinitro-toluene 
• 29682-46-0 2,6-dichloro-3-nitrotoluene 
• 95-49-8 2-methylchlorobenzene 

Downstream Products

• 345618-46-4 (3-chloro-2-methyl-6-nitro-phenyl)-phenyl-amine 
• 673487-36-0 4-chloro-3-methylbenzene-1,2-diamine 
• 132873-82-6 3-Methoxy-2-methyl-6nitrobenzenamine 
• 861552-85-4 4-chloro-3,N²-dimethyl-o-phenylenediamine 
• 131885-98-8 4-Imidazol-1-yl-3-methyl-benzene-1,2-diamine 
• 100959-52-2 7-amino-4-chloroindazole 
• 316810-81-8 4-chloro-7-nitro-1⁽²⁾H-indazole 
• 13290-74-9 1-chloro-2-methyl-4-nitrobenzene 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AND AZA-BENZIMIDAZOLE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF

The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., Janus kinase (JAK), e.g., Janus kinase 2 (JAK2)) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating a disease (e.g., proliferative disease) in a subject in need thereof).

Heterocyclic amines having central nervous system activity

Tricyclic nitrogen containing compounds, having central nervous system activity of the following structural formula: STR1 and pharmaceutically acceptable salts thereof wherein R1, R2, and R3 are independently hydrogen, C1-6 alkyl, alkenyl, or alkynyl, C3-10 cycloalkyl, or R1 and R2 are joined to form a C3-7 cyclic amine which can contain additional heteroatoms; X is hydrogen, C1-6 alkyl halogen, hydroxy, alkoxy, cyano, carboxamide, carboxyl, or carboalkoxyl; A is SO2, N, CH, CH2, CHCH3, C=O, C=S, C-SCH3, C=NH, C-NH2, C-NHCH3, C--NHCOOCH3, or C--NHCN. B is CH2, CH, C=O, N, NH or N--CH3 ; n is 0 or 1; and D is CH, CH2, C=O, O, N, NH or N--CH3. These new compounds are suitable for treating schizophrenia, Parkinson's disease, anxiety, depression or as compounds for lowering blood pressure in animal or human hosts.

N-Phenylpyrazole derivatives

N-Phenylpyrazole derivatives of the formula: STR1 (wherein each of R5 and R6 represents a C1 -C4 alkyl or alkoxy radical, a trifluoromethyl, trifluoromethoxy, nitro, cyano or primary amino radical, or a fluorine, chlorine or bromine atom, each of R7, R8 and R9 represents a hydrogen atom, a C1 -C4 alkyl or alkoxy radical, a trifluoromethyl, trifluoromethoxy, nitro, cyano or primary amino radical or a fluorine, chlorine or bromine atom, or R5, R7, R8 and R9 each represents a hydrogen atom and R6 represents a trifluoromethoxy or trifluoromethyl radical, and R10 represents a cyano radical or substituted carbamoyl radical --CONHR11, wherein R11 represents a methyl or ethyl radical) have been found to possess useful herbicidal properties. All such N-phenylpyrazole derivatives with the exception of 5-amino-4-cyano-1-(2,4-dichlorophenyl)pyrazole and 5-amino-4-cyano-1-(4-chloro-2-methylphenyl)pyrazole are new compounds. Herbicidal compositions containing such N-phenylpyrazole derivatives are described and also processes for the preparation of the new compounds.