51169-57-4

Basic information

• Product Name: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide
• CAS NO: 51169-57-4
• Molecular Formula: C₇H₁₂BrNOS
• Molecular Weight: 238.1453
• Mol File: 51169-57-4.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide(51169-57-4)
• EPA Substance Registry System: 2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide(51169-57-4)

Safety Data

• Hazardous Substances Data: 51169-57-4(Hazardous Substances Data)

Usage

General Description

2-(1-hydroxyethyl)-3,4-dimethyl-1,3-thiazol-3-ium bromide, also known as thioflavin S, is a fluorescent dye commonly used in the study of protein aggregation and amyloid fibrils. It is a cationic dye that binds to beta-sheet-rich structures and exhibits enhanced fluorescence upon binding, making it a valuable tool in the detection and quantification of amyloid aggregates in various biological samples. Thioflavin S has been widely utilized in research related to neurodegenerative diseases such as Alzheimer's and Parkinson's, as well as in the study of other protein misfolding disorders. Its ability to selectively label and visualize amyloid fibrils has made it an important chemical for understanding the pathology of these diseases and for developing potential diagnostic and therapeutic strategies.