5129-61-3

Basic information

• Product Name: 16-METHYLHEPTADECANOIC ACID METHYL ESTER
• Synonyms: METHYL ISOSTEARATE;METHYL 16-METHYLHEPTADECANOATE;Heptadecanoicacid,16-meth;16-Methylheptadecanoic acid methyl ester, Methyl isostearate;16-METHYLHEPTADECANOIC ACID METHYL ESTER
• CAS NO: 5129-61-3
• Molecular Formula: C₁₉H₃₈O₂
• Molecular Weight: 298.5
• Mol File: 5129-61-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 340.7°Cat760mmHg
• Flash Point: 162.2°C
• Appearance: /Liquid
• Density: 0.862g/cm³
• Vapor Pressure: 8.44E-05mmHg at 25°C
• Refractive Index: 1.443
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 16-METHYLHEPTADECANOIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 16-METHYLHEPTADECANOIC ACID METHYL ESTER(5129-61-3)
• EPA Substance Registry System: 16-METHYLHEPTADECANOIC ACID METHYL ESTER(5129-61-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 5129-61-3(Hazardous Substances Data)

Usage

Category

Fatty acid methyl esters

Physical State

Waxy, solid substance

Odor

Odorless

Applications

a. Cosmetic and personal care products (lotions, creams, hair care products)
b. Lubricants
c. Plasticizers
d. Industrial products

Emollient

Enhances the smoothness and softness of the skin

Moisturizing

Helps to retain or increase the skin's moisture content

Antimicrobial

Inhibits the growth of microorganisms

Anti-inflammatory

Reduces inflammation and redness

Popularity

Widely used in skincare formulations due to its beneficial properties

InChI:InChI=1/C19H38O2/c1-18(2)16-14-12-10-8-6-4-5-7-9-11-13-15-17-19(20)21-3/h18H,4-17H2,1-3H3

Upstream product

• 186581-53-3 diazomethane 

Downstream Products

• 2724-58-5 16-methylheptadecanoic acid 
• 41744-75-6 isostearyl Alcohol 

Relevant articles and documents

Mirabolides A and B; new cytotoxic glycerides from the Red Sea sponge Theonella mirabilis

As a part of our continuing work to find out bioactive lead molecules from marine invertebrates, the CHCl3 fraction of the organic extract of the Red Sea sponge Theonella mirabilis showed cytotoxic activity in our primary screen. Bioassay-guided purification of the active fractions of the sponge's extract resulted in the isolation of two new glycerides, mirabolides A and B (1 and 2), together with the reported 4-methylene sterols, conicasterol (3) and swinhosterol B (4). The structures of the compounds were assigned by interpretation of their 1D (1H, 13C), 2D (COSY, HSQC, HMBC, ROESY) NMR spectral data and high-resolution mass determinations. Compounds 1-4 displayed marked cytotoxic activity against human breast adenocarcinoma cell line (MCF-7) with IC50 values of 16.4, 5.18, 6.23 and 3.0 μg/mL, respectively, compared to 5.4 μg/mL observed by doxorubicin as reference drug.