51410-46-9

Basic information

• Product Name: 2-(4-methoxyphenyl)-3-methyloxirane
• Synonyms: 2-(4-methoxyphenyl)-3-methyloxirane;Oxirane, 2-(4-methoxyphenyl)-3-methyl-
• CAS NO: 51410-46-9
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.20108
• Mol File: 51410-46-9.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 251.6°C at 760 mmHg
• Flash Point: 100.1°C
• Appearance: /
• Density: 1.076g/cm³
• Vapor Pressure: 0.0322mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: 2-(4-methoxyphenyl)-3-methyloxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-3-methyloxirane(51410-46-9)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-3-methyloxirane(51410-46-9)

Safety Data

• Hazardous Substances Data: 51410-46-9(Hazardous Substances Data)

Usage

Type of compound

Epoxide derivative.

Parent compound

Eugenol, found in essential oils such as clove oil and cinnamon leaf oil.

Antioxidant

Helps neutralize free radicals and prevent oxidative stress.

Anti-inflammatory

Reduces inflammation in the body.

Anticancer

Shows potential in inhibiting cancer cell growth.

Flavor

Adds a spicy and clove-like taste to food products.

Fragrance

Provides a spicy and clove-like aroma to various products.

Potential use as a biopesticide

Offers a natural alternative to synthetic pesticides in agricultural applications.

InChI:InChI=1/C10H12O2/c1-7-10(12-7)8-3-5-9(11-2)6-4-8/h3-7,10H,1-2H3

Upstream product

• 104-46-1 anethole 
• 4962-31-6 1-(1-acetoxy-2-bromopropyl)-4-methoxybenzene 
• 82947-15-7 2-Bromo-1-(4-methoxy-phenyl)-propan-1-ol 
• 3462-97-3 (4-methoxybenzyl)triphenylphosphonium bromide 
• 25679-28-1 cis-Anethole 
• 256385-72-5 1-(1-hydroxy-2-bromopropyl)-4-methoxybenzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 121-97-1 4-Methoxypropiophenone 
• 55482-46-7 p-methoxypropiophenone morpholine enamine 
• 66823-52-7 α-methyl-α-(methylthio)-p-methoxyacetophenone 
• 74-88-4 methyl iodide 
• 4180-23-8 E-1-(4'-methoxyphenyl)prop-1-ene 
• 768-60-5 4-methoxyphenylacetylen 
• 2749-94-2 1-methoxy-4-(prop-1-yn-1-yl)benzene 

Downstream Products

• 86659-51-0 1-hydroxy-1-(4-methoxyphenyl)propan-2-yl acetate 
• 122-84-9 4-methoxybenzyl methyl ketone 
• 51410-48-1 erythro-anethole glycol 
• 50802-67-0 2-amino-1-(4-methoxyphenyl)propan-1-ol 
• 212394-48-4 1-amino-1-(4-methoxy-phenyl)-propan-2-ol 
• 51410-48-1 (±)-(1R,2R)-1-(4-methoxyphenyl)propane-1,2-diol 
• 51410-48-1 (1SR,2RS)-1-(4-methoxy-phenyl)-propane-1,2-diol 
• 774-41-4 1-bromo-1-(4-methoxyphenyl)propan-2-one 
• 131029-01-1 1-(4-methoxyphenyl)propan-2-ol 
• 106026-88-4 erythro-2-acetoxy-1-(4-methoxyphenyl)-1-phenylthiopropane 
• 934802-56-9 2-[2-hydroxy-1-(4-methoxy-phenyl)-propylamino]-3-phenyl-propan-1-ol 
• 934802-55-8 2-[2-hydroxy-1-(4-methoxy-phenyl)-propylamino]-butan-1-ol 

Relevant articles and documents

Cobalt-Catalyzed Z to e Isomerization of Alkenes: An Approach to (E)-β-Substituted Styrenes

An efficient cobalt-catalyzed Z to E isomerization of β-substituted styrenes using the amido-diphosphine ligand was developed, delivering the (E)-isomers with good functional tolerance and high stereoselectivity. The reaction could be scaled up to gram-scale with a catalyst loading of 0.1 mol %, using a mixture of (Z)- and (E)-alkene as the starting material. Preliminary mechanistic studies indicated that cobalt(I)-hydride and a benzylic-cobalt species were probably involved in the reaction, as supported by experiments and DFT calculations.

Robust and electron deficient oxidovanadium(iv) porphyrin catalysts for selective epoxidation and oxidative bromination reactions in aqueous media

meso-Tetrakis(3,5-dimethoxyphenyl)porphyrinatooxidovanadium (1) and β-octabromo-meso-tetrakis(2,6-dibromo-3,5-dimethoxyphenyl)porphyrinatooxidovanadium (2) were synthesized in excellent yields. The synthesized oxidovanadium(iv) porphyrin complexes were characterized by various spectroscopic methods such as UV-Vis, FT-IR, EPR and MALDI-TOF mass spectrometry, as well as by single crystal X-ray crystallography. The acetonitrile coordinated porphyrin 1 is relatively planar whereas 2 is highly nonplanar as shown by their crystal structures and also by electrochemical studies. Selective epoxidation studies of alkenes were successfully carried out in CH3CN/H2O as the solvent mixture at ambient temperature resulting in very high TOF numbers (12227-14347 h-1 for 2) even with low catalyst loadings. Remarkably, 2 biomimics the vanadium bromoperoxidase (VBrPO) enzyme with extremely high TOF values (83333-87719 h-1) for the oxidative bromination of thymol and some other phenols. Both the catalysts were successfully recovered at the end of the reactions, indicating their viability and industrial applicability.

Umpolung Synthesis of 1,3-Amino Alcohols: Stereoselective Addition of 2-Azaallyl Anions to Epoxides

We report the direct preparation of 1,3-amino alcohols that contain up to three contiguous stereogenic centers by the umpolung coupling of imines and epoxides. Nucleophilic 2-azaallyl anions, generated from imines, are stereoselectively added to epoxides to furnish 1,3-amino alcohols after hydrolysis of the product imine. Transformations afford amino alcohols with >98% site selectivity with respect to both reaction partners and in up to >98% yield and >20:1 dr.