51449-86-6

Basic information

• Product Name: 5-(2-METHYLPHENYL)-1H-TETRAZOLE
• Synonyms: 5-(2-METHYLPHENYL)-1H-TETRAZOLE;5-(o-Tolyl)-1H-tetrazole;5-(2-methylphenyl)-2H-tetrazole(SALTDATA: FREE);5-(2-methylphenyl)-2H-tetrazole
• CAS NO: 51449-86-6
• Molecular Formula: C₈H₈N₄
• Molecular Weight: 160.18
• EINECS: -0
• Mol File: 51449-86-6.mol
• Article Data: 41

Chemical Properties

• Melting Point: 151-154°C
• Boiling Point: 343 °C at 760 mmHg
• Flash Point: 164.4 °C
• Appearance: /
• Density: 1.241 g/cm³
• Vapor Pressure: 7.24E-05mmHg at 25°C
• Storage Temp.: 2-8°C
• PKA: 4.29±0.10(Predicted)
• BRN: 136151
• CAS DataBase Reference: 5-(2-METHYLPHENYL)-1H-TETRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-METHYLPHENYL)-1H-TETRAZOLE(51449-86-6)
• EPA Substance Registry System: 5-(2-METHYLPHENYL)-1H-TETRAZOLE(51449-86-6)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 51449-86-6(Hazardous Substances Data)

Usage

General Description

5-(2-Methylphenyl)-1H-tetrazole is a chemical compound that belongs to the class of organic compounds known as tetrazoles. The tetrazole ring structure, which includes four nitrogen atoms and one carbon atom, is a component of this compound. Additionally, it contains a 2-methylphenyl group. The compound is known for its diversity of uses in various chemical reactions due to its reactive nature. Because of its potential reactivity, safe handling and use require appropriate protective measures. Like most organic compounds, its exact properties (like boiling point, melting point, etc.) can vary based on its precise configuration and purity. Specific information about this compound should be obtained from a reliable source or through laboratory analysis.

InChI:InChI=1/C8H7N4/c1-6-4-2-3-5-7(6)8-9-11-12-10-8/h2-5H,1H3/q-1

Upstream product

• 529-19-1 2-Methylbenzonitrile 
• 16419-60-6 2-Methylphenylboronic acid 
• 79344-08-4 1-benzyl-5-bromo-1H-tetrazole 
• 95-46-5 2-methylphenyl bromide 
• 67-68-5 dimethyl sulfoxide 
• 14683-79-5 salicylaldoxime 
• 529-20-4 2-methylphenyl aldehyde 
• 56280-69-4 2-tributyltin-5-(2-methylphenyl)tetrazole 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 74-88-4 methyl iodide 

Downstream Products

• 138944-19-1 5-(2-hexylphenyl)tetrazole 
• 138944-20-4 5-((2-phenylethyl)phenyl)tetrazole 
• 117594-27-1 N-(4-Nitro-phenyl)-N'-[1-phenyl-1-(5-o-tolyl-tetrazol-1-yl)-meth-(Z)-ylidene]-hydrazine 
• 117594-38-4 N-(4-Nitro-phenyl)-N'-[1-phenyl-1-(5-o-tolyl-tetrazol-2-yl)-meth-(Z)-ylidene]-hydrazine 
• 69746-34-5 2-methyl-5-(2-methylphenyl)-2H-tetrazole 
• 77455-50-6 1-Methyl-5-o-tolyl-1H-tetrazole 
• 138944-18-0 5-(2-ethylphenyl)tetrazole 

Relevant articles and documents

On the relative strength of the 1H-tetrazol-5-yl- and the 2-(triphenylmethyl)-2H-tetrazol-5-yl-group in directed ortho-lithiation

ortho-Lithiation followed by electrophilic trapping of N-unsubstituted and N2-triphenylmethyl substituted 5-aryltetrazoles, further substituted with another ortho-director at the para position of the aryl ring, resulted in the formation of regioisomers of

Synthesis, structure, and antiviral properties of novel 2-adamantyl-5-aryl-2H-tetrazoles

[Figure not available: see fulltext.] The reaction of 5-aryl-NH-tetrazoles with adamantan-1-ol in concentrated sulfuric acid proceeds regioselectively with the formation of the corresponding 2-adamantyl-5-aryl-2H-tetrazoles. Nitration of these compounds l

One-Pot Suzuki-Hydrogenolysis Protocol for the Modular Synthesis of 2,5-Diaryltetrazoles

2,5-Diaryltetrazoles are a diverse range of compounds of considerable interest within the field of photochemistry as a valuable precursor of the nitrile imine 1,3-dipole. Current literature approaches toward this heterocycle remain unsuitable for the prac

Synthesis, molecular docking and xanthine oxidase inhibitory activity of 5-aryl-1H-tetrazoles

5-Aryl-1H-tetrazoles (1–24) were synthesized and screened for their xanthine oxidase (XO) inhibitory activity using allopurinol as standard inhibitor (IC50 = 2.0 ± 0.01 μM). Six compounds 3, 4, 5, 9, 21, and 24 exhibited significant to weak act