51467-70-0Relevant articles and documents
Microwave-assisted reduction of aromatic nitro compounds with novel oxo-rhenium complexes
Blacque, Olivier,Grieco, Gabriele
, (2021/09/16)
The reduction of several aromatic nitro compounds to amines by means of the two novel catalytic systems ([IMes]2ReOBr3)/PhSiH3 and ([Py]3ReNOBr2)/PhSiH3 under microwave irradiation is here reported. These two systems were able to perform the reduction of nitro groups with higher TON and TOF when compared with previously reported systems based on oxo-rhenium core under standard heating, although they showed a lesser broad reaction scope compared with the known systems.
Purin-8-ones as corticotropin-releasing hormone (CRH-R1) receptor antagonists
Beck, James P.,Arvanitis, Argyrios G.,Curry, Matt A.,Rescinito, Joseph T.,Fitzgerald, Larry W.,Gilligan, Paul J.,Zaczek, Robert,Trainor, George L.
, p. 967 - 972 (2007/10/03)
A series of purin-8-ones was prepared and discovered to have excellent binding affinity to the CRH-R1 receptor. Structure-activity studies focused on amine side-chain optimization, urea substitution and pyridyl isostere incorporation. Thus, the highly potent purin-8-ones show promise as a new class of potential anxiolytics and/or antidepressants.
THE EFFECT OF VICINAL METHYL GROUPS ON THE REDUCTION OF AROMATIC NITRO COMPOUNDS WITH LITHIUM ALUMINIUM HYDRIDE
Puszynski, Andrzej,Rykowski, Zbigniew,Gubrynowicz, Olaf
, p. 805 - 808 (2007/10/02)
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