51581-47-6 Usage
General Description
1-(2-Chlorophenyl)imidazoline-2-thione, also known as CL 288859, is a chemical compound with the molecular formula C9H8ClN3S. It is a thioether derivative of imidazolidine, which has been identified as a potential angiotensin II receptor antagonist. It has demonstrated antihypertensive and antiarrhythmic activities in animal studies, and has been investigated for its potential use in the treatment of hypertension and cardiac arrhythmias. Additionally, research has shown that 1-(2-chlorophenyl)imidazoline-2-thione may possess anti-inflammatory and antiviral properties, indicating potential therapeutic applications in these areas as well.
Check Digit Verification of cas no
The CAS Registry Mumber 51581-47-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,8 and 1 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 51581-47:
(7*5)+(6*1)+(5*5)+(4*8)+(3*1)+(2*4)+(1*7)=116
116 % 10 = 6
So 51581-47-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2S/c10-7-3-1-2-4-8(7)12-6-5-11-9(12)13/h1-6H,(H,11,13)
51581-47-6Relevant articles and documents
Structure activity relationships in reactivators of organophosphorus inhibited acetylcholinesterase. VII. 1 Aryl 2 hydroxyiminomethyl 3 methylimidazolium iodides
Franchetti,Grifantini,Martelli,Stein
, p. 18 - 22,21,22 (2007/10/05)
A series of 1 aryl 2 hydroxyiminomethyl 3 methylimidazolium iodides, where the aryl group is either phenyl or substituted phenyl, was prepared and tested for their reactivating potency on phosphorylated acetylcholinesterase (AChE) and for anti AChE activity. The in vitro testing revealed that some of the new compounds are good reactivators. Correlations between their structure and biological activities have been attempted.
