51649-35-5

Basic information

• Product Name: 2H-Isoindole,4,5,6,7-tetrahydro-(9CI)
• Synonyms: 2H-Isoindole,4,5,6,7-tetrahydro-(9CI);4,5,6,7-Tetrahydroisoindole;4,5,6,7-Tetrahydro-2H-isoindole
• CAS NO: 51649-35-5
• Molecular Formula: C₈H₁₁N
• Molecular Weight: 121.182
• Product Categories: PYRROLIDINE
• Mol File: 51649-35-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 253.3±9.0 °C(Predicted)
• Appearance: /
• Density: 1.057±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 17.60±0.20(Predicted)
• CAS DataBase Reference: 2H-Isoindole,4,5,6,7-tetrahydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole,4,5,6,7-tetrahydro-(9CI)(51649-35-5)
• EPA Substance Registry System: 2H-Isoindole,4,5,6,7-tetrahydro-(9CI)(51649-35-5)

Safety Data

• Hazardous Substances Data: 51649-35-5(Hazardous Substances Data)

Usage

General Description

2H-Isoindole,4,5,6,7-tetrahydro-(9CI) is a chemical compound with a cyclic structure, consisting of four carbon atoms and one nitrogen atom arranged in a ring. It is classified as a heterocyclic compound and is also known as tetrahydroisoindole. 2H-Isoindole,4,5,6,7-tetrahydro-(9CI) has various applications, including in the production of pharmaceuticals, agrochemicals, and organic synthesis. It is a versatile building block for the synthesis of various other organic compounds, due to its unique structure and reactivity. Additionally, 2H-Isoindole,4,5,6,7-tetrahydro-(9CI) has also been studied for its potential biological activities, making it an interesting target for further research and development.

Upstream product

• 188258-07-3 4,5,6,7-Tetrahydro-2H-isoindole-1-carboxylic acid butyl ester 
• 65880-17-3 ethyl 4,5,6,7-tetrahydro-2H-isoindole-1-carboxylate 
• 930-68-7 cyclohexenone 
• 110-83-8 cyclohexene 
• 122181-89-9 2-((5'-carbomethoxy-4'-pentynoyl)amino)-4,5,6,7-tetrahydro-2H-isoindole 
• 122181-81-1 2-phthalimido-4,5,6,7-tetrahydro-2H-isoindole 
• 122181-82-2 2-amino-4,5,6,7-tetrahydro-2H-isoindole 
• 51555-65-8 cyclohexane-1,2-dicarbaldehyde 
• 100388-85-0 (2-Chloro-cyclohexanesulfonyl)-benzene 
• 14032-03-2 1-chloro-2-phenylsulfanylcyclohexane 
• 931-59-9 benzenesulfenyl chloride 
• 33995-48-1 trans-2-chlorocyclohexyl phenyl sulfone 
• 14032-03-2 ((1R,2R)-2-chlorocyclohexyl)(phenyl)sulfane 
• 59059-70-0 1-(phenylsulfonyl)cyclohexene 

Downstream Products

• 172959-71-6 2,5-bis<<5-(benzyloxycarbonyl)-3-ethyl-4-methylpyrrol-2-yl>methyl>-3,4-butanopyrrole 
• 1287673-74-8 (5,10,15-triphenyl-2:3,7:8,12:13,17:18-tetrabutanocorrolato)copper 
• 1426521-09-6 C₁₅H₁₈N₂ 
• 1613627-43-2 C₁₅H₁₄N₂ 
• 865479-43-2 5,5-difluoro-3,7-dimethyl-10-phenyl-5H-4λ⁴,5λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine 

Relevant articles and documents

Porphyrins with Exocyclic Rings. Part 8 [1], Synthesis of Nitrogen-15 and Carbon-13 Labeled 2,3:7,8:12,13:17,18-Tetrabutanoporphyrin [2,3]

Nitrogen-15 labeled butyl 4,5,6,7-tetrahydro-2H-isoindole-1-carboxylate was prepared via butyl isocyanoacetate from 15N-glycine in an overall 46% yield, This bicyclic intermediate was converted into nitrogen-15 and carbon-13 labeled 2,3:7,8:12, 13:17, 18-tetrabutanoporphyrin, a useful model system for the sedimentary tetrahydrobenzoporphyrins.

TAMBJAMINES AND B-RING FUNCTIONALIZED PRODIGININES

Embodiments of tambjamines and B-ring functionalized prodiginines are disclosed. Methods of synthesizing and using the disclosed compounds are also disclosed. Some embodiments of the disclosed compounds have antimalarial activity. Certain embodiments of t

GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).

Synthesis and Structure-Activity Relationships of Tambjamines and B-Ring Functionalized Prodiginines as Potent Antimalarials

Synthesis and antimalarial activity of 94 novel bipyrrole tambjamines (TAs) and a library of B-ring functionalized tripyrrole prodiginines (PGs) against a panel of Plasmodium falciparum strains are described. The activity and structure-activity relationsh