51727-05-0 Usage
General Description
5,6-DIMETHYL-2-OXO-1,2-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID, also known as Niacin or Vitamin B3, is a water-soluble vitamin that plays a crucial role in the metabolism of carbohydrates, fats, and proteins. It is essential for the production of energy in the body and is involved in DNA repair and synthesis. Niacin also helps maintain the health of the skin, digestive system, and nervous system. Deficiency in this compound can lead to a condition known as pellagra, which is characterized by skin rashes, diarrhea, and dementia. It is commonly found in various foods such as meat, fish, nuts, and whole grains, and can also be taken as a dietary supplement to prevent or treat niacin deficiency.
Check Digit Verification of cas no
The CAS Registry Mumber 51727-05-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,7,2 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 51727-05:
(7*5)+(6*1)+(5*7)+(4*2)+(3*7)+(2*0)+(1*5)=110
110 % 10 = 0
So 51727-05-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO3/c1-4-3-6(8(11)12)7(10)9-5(4)2/h3H,1-2H3,(H,9,10)(H,11,12)
51727-05-0Relevant articles and documents
Preparation process of 5,6-dimethyl-2-hydroxynicotinic acid
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Paragraph 0025; 0026, (2018/04/02)
The invention provides a preparation process of 5,6-dimethyl-2-hydroxynicotinic acid 1. The preparation process of 5,6-dimethyl-2-hydroxynicotinic acid comprises the following steps: 1) performing a reaction on 2-butanone and ethyl formate in a proper solvent, under the existence of alkali and at proper temperature to obtain a compound 2; 2) performing condensation on the compound 2 and cyanoacetamide in a proper solvent and at proper temperature to obtain a compound 3; and 3) performing cyan-hydrolysis on the compound 3 under the existence of diluted acid to obtain 5,6-dimethyl-2-hydroxynicotinic acid 1. The synthesis route is as shown in the description. In the preparation process, the raw materials, the reagents and the solvents are the conventional synthesis reagents, and are cheap andeasily available; and the reaction condition of each step is mild, the aftertreatment operation is simple, the reaction yield is high and the product purity is high. The whole preparation cost of theproducts is low and the industrial production requirement is met.
