51746-87-3

Basic information

• Product Name: 4-(1H-IMIDAZOL-4-YL)-PYRIDINE
• Synonyms: 4-(1H-IMIDAZOL-4-YL)-PYRIDINE;4-(1H-IMidazol-5-yl)pyridine;4-(4-Pyridyl)imidazole;Pyridine, 4-(1H-iMidazol-4-yl)-;4-(1H-imidazole-4-yl)pyridine
• CAS NO: 51746-87-3
• Molecular Formula: C8H7N3
• Molecular Weight: 145.16128
• Product Categories: Heterocycle-Pyridine series
• Mol File: 51746-87-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 195-196℃ (acetone hexane )
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(1H-IMIDAZOL-4-YL)-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1H-IMIDAZOL-4-YL)-PYRIDINE(51746-87-3)
• EPA Substance Registry System: 4-(1H-IMIDAZOL-4-YL)-PYRIDINE(51746-87-3)

Safety Data

• Hazardous Substances Data: 51746-87-3(Hazardous Substances Data)

Usage

General Description

4-(1H-Imidazol-4-yl)-pyridine, also known as I4P, is a chemical compound with the molecular formula C9H7N3. It is a derivative of pyridine and imidazole, and it is commonly used as a building block for the synthesis of pharmaceuticals and agrochemicals. 4-(1H-IMIDAZOL-4-YL)-PYRIDINE has been widely studied for its potential pharmacological properties, including its ability to interact with various biological targets such as receptors and enzymes. 4-(1H-Imidazol-4-yl)-pyridine is also known for its potential antifungal and antibacterial activities, making it a valuable compound in the field of medicinal chemistry and drug discovery.

Upstream product

• 167897-35-0 4-(4-pyridyl)imidazole-2-thione hydrochloride 
• 73286-33-6 4-(α-aminoacetyl)pyridine dihydrochloride 
• 167897-36-1 2-(4-pyridyl)-2,2-dimethoxyethylamine dihydrochloride 
• 71759-89-2 4-iodoimidazole 
• 1692-15-5 4-pyridylboronic acid 

Relevant articles and documents

A convenient synthesis of 4(5)-(hetero)aryl-1H-imidazoles via microwave-assisted Suzuki-Miyaura cross-coupling reaction

A simple and rapid access to a variety of 4(5)-arylated imidazoles via palladium-catalyzed Suzuki-Miyaura cross-coupling reaction is described. Coupling parameters were screened for efficient C-4 arylation of N-unprotected 4-iodoimidazole with a broad range of boronic acids under microwave irradiation. Twenty-one imidazole derivatives were synthesized in modest to excellent yields in short reaction times.

Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists

The present invention relates to a novel process for the preparation of highly potent histamine receptor antagonists, in particular histamine H 3 receptor antagonists. Also disclosed is a novel process for the preparation of intermediates useful in the preparation of histamine receptor antagonists, in particular H 3 -receptor antagonists.

Piperidine derivatives, their preparation and their therapeutic application

A compound which is a piperidine derivative of general formula (I) STR1 in which R 1 represents a hydrogen atom, a linear or branched (C 1-6)alkyl group or a cyclo(C 3-8)alkyl group, X represents an oxygen atom, a sulphur atom or a group of general formul