52095-40-6

Basic information

• Product Name: Ethanone, 1-(2-ethenylphenyl)- (9CI)
• Synonyms: Ethanone, 1-(2-ethenylphenyl)- (9CI)
• CAS NO: 52095-40-6
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146.1858
• Product Categories: ACETYLGROUP
• Mol File: 52095-40-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 241°Cat760mmHg
• Flash Point: 95.4°C
• Appearance: /
• Density: 0.995g/cm³
• Vapor Pressure: 0.0367mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: Ethanone, 1-(2-ethenylphenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-ethenylphenyl)- (9CI)(52095-40-6)
• EPA Substance Registry System: Ethanone, 1-(2-ethenylphenyl)- (9CI)(52095-40-6)

Safety Data

• Hazardous Substances Data: 52095-40-6(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2-ethenylphenyl)- is a chemical compound identified by the Chemical Abstracts Service (CAS) as 1-(2-ethenylphenyl)ethan-1-one or 1-(2-vinylphenyl)ethanone. Ethanone, 1-(2-ethenylphenyl)- (9CI) contains a ketone group attached to a phenyl ring, with an ethenyl functional group located at the 2-position of the phenyl ring. It has applications in various industries including pharmaceuticals, dyes, and fragrances. Its specific properties and potential uses would depend on its purity and synthesis method. Further research and testing may be needed to fully understand its potential benefits and risks in different applications.

InChI:InChI=1/C10H10O/c1-3-9-6-4-5-7-10(9)8(2)11/h3-7H,1H2,2H3

Upstream product

• 7486-35-3 tri-n-butyl(vinyl)tin 
• 129849-05-4 trifluoromethanesulfonic acid 2-acetylphenyl ester 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 77-78-1 dimethyl sulfate 
• 4363-34-2 vinylboronic acid 
• 2142-69-0 2-bromophenyl methyl ketone 
• 118-93-4 o-hydroxyacetophenone 
• 613-91-2 acetophenone oxime 
• 75927-49-0 pinacol vinylboronate 
• 74-85-1 ethene 
• 2142-70-3 2-iodoacetophenone 
• 90766-20-4 1-ethynyl-2-vinylbenzene 
• 141791-38-0 1-ethenyl-2-[2-(trimethylsilyl)ethynyl]benzene 
• 1588511-51-6 N-methoxy-N-methyl-2-vinylbenzamide 

Downstream Products

• 1721-93-3 1-methylisoquinoline 
• 84810-24-2 2-[2-(acetyl)phenyl] propanoic acid 
• 1621190-61-1 methanesulfonic acid [1-{2-[3-(2-{1-[2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)acetyl]piperidin-4-yl}thiazol-4-yl)-4,5-dihydro-isoxazol-5-yl]-phenyl}ethylidene]hydrazide 
• 1621190-76-8 methanesulfonic acid [1-{2-[3-(2-chloro-acetyl)-4,5-dihydro-isoxazol-5-yl]phenyl}ethylidene]hydrazide 
• 1313009-34-5 1-[4-[4[-5-(2-acetylphenyl)-4,5-dihydroisoxazol-3-yl]thiazol-2-yl]-1-piperidyl]-2-[3,5-bis(difluoromethyl)pyrazol-1-yl]ethanone 
• 1621190-75-7 methanesulfonic acid [1-(2-vinyl-phenyl)ethylidene]hydrazide 
• 1313009-88-9 tert-butyl 4-{4-[5-(2-acetylphenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidine-1-carboxylate 
• 201863-16-3 (P(C₆H₅)3)2Ru(CO)(CH₃COC₆H₄CHCH₂) 
• 10240-08-1 4-methyl-1-naphthol 

Relevant articles and documents

Intramolecular One-Carbon Homologation of Unstrained Ketones via C-C Activation-Enabled 1,1-Insertion of Alkenes

Here, we describe the development of a Rh-catalyzed intramolecular one-carbon homologation of unstrained aryl ketones through a formal 1,1-insertion process of olefins, enabled by temporary directing group (TDG)-aided C-C activation. The reaction provides a distinct approach to access various substituted 1-indanones. Computational mechanistic studies reveal that the formal 1,1-insertion is realized by a selective C(sp2)-C(sp3) activation and turnover limiting 2,1-insertion into the alkene, followed by a facile β-H elimination and reinsertion process.

Rhodium-Catalyzed Hydrocarboxylation of Olefins with Carbon Dioxide

The catalytic hydrocarboxylation of styrenes derivatives and α,β-unsaturated carbonyl compounds with CO2(101.3 kPa) in the presence of an air-stable rhodium catalyst was explored. The combination of [RhCl(cod)]2(cod = cyclooctadiene) as a catalyst and diethylzinc as a hydride source allowed for effective hydrocarboxylation and provided the corresponding α-aryl carboxylic acids in moderate to excellent yields. In this catalytic process with carbon dioxide, intervention of the RhI–H species, which could be generated from the RhIcatalyst and diethylzinc, was clarified. Significantly, the catalytic asymmetric hydrocarboxylation of α,β-unsaturated esters with carbon dioxide was also performed by employing a cationic rhodium complex possessing (S)-(–)-4,4′-bi-1,3-benzodioxole-5,5′-diylbis(diphenylphosphine) [(S)-SEGPHOS] as a chiral diphosphine ligand. A plausible model for asymmetric induction was proposed by determination of the absolute configuration of the product.

One-pot Suzuki/Heck sequence for the synthesis of (E)-stilbenes featuring a recyclable silica-supported palladium catalyst via a multi-component reaction in 1,3-propanediol

The synthesis of (E)-stilbenes was performed following a one-pot Suzuki/Heck sequence through the use of potassium vinyltrifluoroborate. The combination of heterogeneous palladium/silica (Pd/SiO2) catalyst with potassium phosphate monohydrate (K3PO4?H 2O) as base resulted in useful to good isolated yields regardless of the ortho-, meta- or para-substitution of the aryl halides employed. In a sustainable approach, we found that bio-sourced 1,3- propanediol could advantageously replace N-methylpyrrolidone (NMP) as similar yields were obtained. Moreover, the reactivity gap between aryl iodides and bromides resulting from the use of 1,3-propanediol allowed an efficient multi-component approach toward the synthesis of (E)-stilbenes. Furthermore, this heterogeneous catalyst was found to be extremely robust despite the use of aerobic conditions and was successfully re-used over several cycles.