5211-44-9

Basic information

• Product Name: 2,3,5,6-tetrafluoro-4-mercapto-Benzoic acid
• Synonyms: 2,3,5,6-tetrafluoro-4-mercapto-Benzoic acid;2,3,5,6-tetrafluoro-4-sulfanyl-benzoic acid
• CAS NO: 5211-44-9
• Molecular Formula: C₇H₂F₄O₂S
• Molecular Weight: 226.15
• Mol File: 5211-44-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 153 °C
• Boiling Point: 273.3°Cat760mmHg
• Flash Point: 119.1°C
• Appearance: /
• Density: 1.72g/cm³
• Vapor Pressure: 0.00282mmHg at 25°C
• Refractive Index: 1.541
• Solubility: soluble in Methanol
• CAS DataBase Reference: 2,3,5,6-tetrafluoro-4-mercapto-Benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5,6-tetrafluoro-4-mercapto-Benzoic acid(5211-44-9)
• EPA Substance Registry System: 2,3,5,6-tetrafluoro-4-mercapto-Benzoic acid(5211-44-9)

Safety Data

• Hazardous Substances Data: 5211-44-9(Hazardous Substances Data)

Usage

General Description

2,3,5,6-tetrafluoro-4-mercapto-Benzoic acid is a chemical compound that, as its name suggests, possesses both fluoro and mercapto functional groups on a benzoic acid backbone. The compound is an organic derivative of benzoic acid, a simple aromatic carboxylic acid. 2,3,5,6-tetrafluoro-4-mercapto-Benzoic acid is a strong acid due to presence of fluorine atoms, which are highly electronegative. It's fluorine groups contribute to the molecule having a significant polarity and also impact its reactivity. Furthermore, the mercapto group (-SH) may make the compound a good ligand, potentially engaging in positive interactions with transition metals in certain conditions. The exact properties, however, could be varying depending on the specific conditions and reagents it interacts with.

InChI:InChI=1/C7H2F4O2S/c8-2-1(7(12)13)3(9)5(11)6(14)4(2)10/h14H,(H,12,13)

Upstream product

• 602-94-8 Pentafluorobenzoic acid 
• 771-62-0 pentafluorophenylthiol 
• 124-38-9 carbon dioxide 
• 769-40-4 2,3,5,6-tetrafluorothiophenol 
• 70-18-8 GLUTATHIONE 
• 327-54-8 1,2,4,5-Tetrafluorobenzene 
• 652-18-6 2,3,5,6-tetrafluorobenzoic acid 
• 7704-34-9 sulfur 
• 363-72-4 Pentafluorobenzene 

Downstream Products

• 125662-60-4 4-sulpho-2,3,5,6-tetrafluorobenzoic acid 
• 145572-18-5 ethylene glycol bis-(4-fluorosulphonyl-2,3,5,6-tetrafluorobenzoate) 
• 145572-20-9 methyl 4-N-phenylaminosulphonyl-2,3,5,6-tetrafluorobenzoate 
• 145572-17-4 4-chlorosulphonyl-2,3,5,6-tetrafluorobenzanilide 
• 145588-27-8 4-fluorosulphonyl-2,3,5,6-tetrafluorobenzanilide 
• 145572-16-3 methyl 4-chlorosulphonyl-2,3,5,6-tetrafluorobenzoate 
• 145572-15-2 methyl 4-fluorosulphonyl-2,3,5,6-tetrafluorobenzoate 
• 145572-13-0 4-trifluoromethyl-2,3,5,6-tetrafluorobenzenesulphonyl fluoride 
• 145572-12-9 4-(chlorosulfonyl)-2,3,5,6-tetrafluorobenzoyl chloride 
• 145572-14-1 4-fluorosulphonyl-2,3,5,6-tetrafluorobenzoic acid 
• 145572-11-8 4-chloro-2,3,5,6-tetrafluoro-N-benzanilide 
• 89847-85-8 methyl 4-chloro-2,3,5,6-tetrafluorobenzoate 
• 145572-10-7 4-chloro-2,3,5,6-tetrafluorobenzoyl chloride 
• 145588-26-7 4-chloro-2,3,5,6-tetrafluorobenzoyl fluoride 

Relevant articles and documents

Quantitative determination of SH groups using 19F NMR spectroscopy and disulfide of 2,3,5,6-tetrafluoro-4-mercaptobenzoic acid

A new method of measurement of thiol concentration by 19F NMR spectroscopy is developed. The method is based on the detection of products of the exchange reaction of thiols with a newly synthesized fluorinated disulfide, 2,3,5,6-tetrafluoro-4-mercaptobenzoic acid (BSSB). A significant broadening of the 19F NMR signal of BSSB in the presence of thiols was observed and attributed to the exchange reaction between the parent disulfide and 2,3,5,6-tetrafluoro-4-mercaptobenzoic acid. The rate constant for this reaction was found to be equal to (63 ± 11) × 103 M-1 s-1 at pH 7.0. The method was applied for the measurement of concentration of glutathione and albumin in rat blood. Copyright