52120-10-2

Basic information

• Product Name: N,N'-di-n-butyl-benzamidine
• Synonyms: N,N'-di-n-butyl-benzamidine
• CAS NO: 52120-10-2
• Molecular Weight: 232.369
• Mol File: 52120-10-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N'-di-n-butyl-benzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-di-n-butyl-benzamidine(52120-10-2)
• EPA Substance Registry System: N,N'-di-n-butyl-benzamidine(52120-10-2)

Safety Data

• Hazardous Substances Data: 52120-10-2(Hazardous Substances Data)

Upstream product

• 936-61-8 Thiobenzoic acid O-ethyl ester 
• 109-73-9 N-butylamine 
• 15421-91-7 N'-(n-butyl)phenylamidine 
• 100-47-0 benzonitrile 
• 1246287-59-1 C₁₄H₁₄N₄O₂ 
• 618-39-3 benzamidin 
• 109-72-8 n-butyllithium 
• 4222-25-7 3-bromo-3-phenyl-3H-diazirine 
• 825-60-5 benzimidic acid ethyl ester 

Relevant articles and documents

Radical and Nitrenoid Reactivity of 3-Halo-3-phenyldiazirines

3-Halo-3-phenyl-3H-diazirines (halogen = Br or Cl) undergo a dissociative single-electron transfer from alkyllithiums (RLi) in THF-based solvent mixtures. The resulting 3-phenyldiazirinyl radical, observed by EPR spectroscopy, is eventually transformed to benzonitrile. In Et2O, 2 equiv of RLi add to both nitrogens of halodiazirine N=N bond, affording N,N′-dialkylbenzamidines. The nitrenoid reactivity of some N-alkyl-1H-diazirine intermediates is manifested by their insertion into the α-C-H bond of THF or Et2O.

Samarium diiodide promoted synthesis of N,N′-disubstituted amidines

An efficient one-step preparation of an N,N′-disubstituted amidine by the direct nucleophilic addition of an amine to the parent nitrile using catalytic amounts of SmI2 under relatively mild conditions is developed. Alkyl, benzyl and aryl amidi