52128-85-5

Basic information

• Product Name: 3H-Pyrazol-3-one, 1,2-dihydro-5-methyl-1,2-diphenyl-
• CAS NO: 52128-85-5
• Molecular Formula: C16H14N2O
• Molecular Weight: 250.3
• Mol File: 52128-85-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3H-Pyrazol-3-one, 1,2-dihydro-5-methyl-1,2-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3H-Pyrazol-3-one, 1,2-dihydro-5-methyl-1,2-diphenyl-(52128-85-5)
• EPA Substance Registry System: 3H-Pyrazol-3-one, 1,2-dihydro-5-methyl-1,2-diphenyl-(52128-85-5)

Safety Data

• Hazardous Substances Data: 52128-85-5(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 122-66-7 diphenyl hydrazine 
• 674-82-8 4-methyleneoxetan-2-one 
• 108-24-7 acetic anhydride 

Downstream Products

• 109725-19-1 4-acetyl-5-methyl-1,2-diphenyl-1,2-dihydro-pyrazol-3-one 
• 101444-59-1 5-methyl-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazole-4-carbaldehyde 
• 257920-61-9 4-amino-5-methyl-1,2-diphenyl-1,2-dihydro-3H-pyrazol-3-one 
• 23582-71-0 (5-methyl-3-oxo-1,2-diphenyl-2,3-dihydro-1H-pyrazol-4-yl)-acetic acid 
• 102-01-2 N-phenylacetoacetamide 
• 62-53-3 aniline 

Relevant articles and documents

Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics

To develop novel nonallergenic pyrazolone analgesics, we synthesized a series of compounds in which position 1 of the pyrazolone ring was substituted in place of the original methyl group in order to block the formation of allergenic metabolites via N-dea

NOVEL UREIDO - AND AMIDO-PYRAZOLONE DERIVATIVES

The present invention provides compounds of formula (I); wherein each of R1 to R4 is independently selected from hydrogen, a halogen, a substituted or unsubstituted cyclic and heterocyclic moiety, substituted or unsubstituted, linear or branched alkyl, alkyloxy, alkylcarbonyl, alkyloxycarbonyl, alkenyl, alkenyloxy, alkenylcarbonyl, alkenyloxycarbonyl, alkynyl, alkynyloxy, alkynylcarbonyl, alkynyloxycarbonyl, aryl, benzyl, arlyoxy, arylcarbonyl, aryloxycarbonyl and sulphur equivalents of said oxy, carbonyl and oxycarbonyl moieties, and A is NH, or (CH2)n, where n is preferably 0, 1 or 2. The invention also relates to methods for preparing the compounds and their uses as CCK receptor ligands and CCK antagonists.