522608-86-2

Basic information

• Product Name: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL
• Synonyms: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL;N-benzyl-3-azabicyclo[3.2.1]octan-8β-ol;(8-anti)-3-benzyl-3-azabicyclo[3.2.1]octan-8-ol
• CAS NO: 522608-86-2
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.31
• Mol File: 522608-86-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 103-104 °C
• Boiling Point: 353.7±22.0 °C(Predicted)
• Appearance: /
• Density: 1.147±0.06 g/cm3(Predicted)
• PKA: 14?+-.0.20(Predicted)
• CAS DataBase Reference: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL(522608-86-2)
• EPA Substance Registry System: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL(522608-86-2)

Safety Data

• Hazardous Substances Data: 522608-86-2(Hazardous Substances Data)

Usage

General Description

3-Benzyl-3-azabicyclo[3.2.1]octan-8-ol is a chemical compound with a complex and unique structure. It contains a benzyl group and an azabicyclooctane ring, which contributes to its characteristic pharmacological and biological properties. 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-OL is a tertiary amine and an alcohol, making it potentially useful for a variety of synthetic and medicinal applications. Its specific chemical structure and composition make it an interesting target for further research and development in the fields of organic chemistry and pharmaceuticals.

Upstream product

• 83507-33-9 3-benzyl-3-aza-bicyclo[3.2.1]octan-8-one 
• 882188-60-5 3-benzyl-3-azabicyclo[3.2.1]octan-8-ol 
• 521944-15-0 N-benzyl-3-azabicyclo[3.2.1]octan-8α-ol 
• 521944-35-4 N-benzyl-3-azabicyclo[3.2.1]octane-8α-yl trifluoromethanesulfonate 

Downstream Products

• 521944-35-4 N-benzyl-3-azabicyclo[3.2.1]octane-8α-yl trifluoromethanesulfonate 
• 866615-21-6 N-benzyl-8β-[2-propoxy-4-(trifluoromethyl)phenoxy]-3-azabicyclo[3.2.1]octane 
• 934001-71-5 3-azabicyclo[3.2.1]octan-8-ol 

Relevant articles and documents

PROGRANULIN MODULATORS AND METHODS OF USING THE SAME

Provided herein are compounds that modulate progranulin and methods of using the compounds in progranulin-associated disorders, such as Frontotemporal dementia (FTD).

PROCESS FOR PRODUCTION OF AZABICYCLOALKANOL DERIVATIVE

The object is to produce an azabicycloalkanol derivative, particularly a cis-3-substituted-3-azabicyclo[3.2.1]octan-8-ol derivative which is a useful intermediate for agricultural chemicals or pharmaceutical agents, with a good yield and at an industrially low cost. A diastereomer of an azabicyclo-C6-10-alkanol derivative having a methyne substituted a hydroxyl group as an asymmetric carbon (e.g., a trans-3-substituted-3-azabicyclo[3.2.1]-8-ol derivative) is isomerized in the presence of a transition metal complex, thereby producing an excess amount of a thermodynamically more stable one of diastereomers (e.g., a cis-3-substituted-3-azabicyclo[3.2.1]-8-ol derivative). In this manner, a thermodynamically more stable one of diastereomers of the azabicyclo-C6-10-alkanol derivatives can be produced.