52751-53-8Relevant articles and documents
Total Synthesis of (±)-Phyllantidine: Development and Mechanistic Evaluation of a Ring Expansion for Installation of Embedded Nitrogen-Oxygen Bonds
Cox, Joshua B.,Jackson, Amy C.,Lambert, Kyle M.,Liu, Lin,Wiberg, Kenneth B.,Wood, John L.,Yruegas, Sam
, p. 9757 - 9766 (2020/05/25)
The development of a concise total synthesis of (±)-phyllantidine (1), a member of the securinega family of alkaloids containing an unusual oxazabicyclo[3.3.1]nonane core, is described. The synthesis employs a unique synthetic strategy featuring the ring
