52756-36-2

Basic information

• Product Name: 4-tert-butyl-3-chlorobenzenamine
• Synonyms: 4-tert-butyl-3-chlorobenzenamine
• CAS NO: 52756-36-2
• Molecular Formula: C₁₀H₁₄ClN
• Molecular Weight: 183.67786
• Mol File: 52756-36-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 142-144 °C(Press: 10 Torr)
• Appearance: /
• Density: 1.078±0.06 g/cm3(Predicted)
• PKA: 3.87±0.10(Predicted)
• CAS DataBase Reference: 4-tert-butyl-3-chlorobenzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-butyl-3-chlorobenzenamine(52756-36-2)
• EPA Substance Registry System: 4-tert-butyl-3-chlorobenzenamine(52756-36-2)

Safety Data

• Hazardous Substances Data: 52756-36-2(Hazardous Substances Data)

Usage

General Description

4-tert-butyl-3-chlorobenzenamine is a chemical compound with the molecular formula C10H14ClN. It is a derivative of aniline, containing a tert-butyl group and a chlorine atom attached to a benzene ring. 4-tert-butyl-3-chlorobenzenamine is commonly used in organic synthesis and pharmaceutical intermediates. It is known for its potential as a building block for the synthesis of various pharmaceutical drugs, agrochemicals, and specialty chemicals. Additionally, 4-tert-butyl-3-chlorobenzenamine is also utilized as a precursor in the production of dyes and pigments. Its properties and structure make it a versatile chemical with several potential applications in various fields.

Upstream product

• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 
• 3282-56-2 4-tert-butylnitrobenzene 
• 52756-38-4 1-(tert-butyl)-2-chloro-4-nitrobenzene 
• 103392-84-3 2-tert-Butyl-5-nitro-phenylamine 

Downstream Products

• 1452184-10-9 4-tert-butyl-3-chlorobenzene-1-sulfonyl chloride 
• 1452182-86-3 4-tert-butyl-3-chloro-N-(3-methyl-1-(quinolin-5-yl)-1H-pyrazol-5-yl)benzenesulfonamide 

Relevant articles and documents

Discovery of orally efficacious RORγt inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds

A series of novel phenylglycinamides as retinoic acid receptor-related orphan receptor-gamma t (RORγt) inverse agonists were discovered through optimization of a high-throughput screen hit 1. (R)-N-(2-((3,5-Difluoro-4-(trimethylsilyl)phenyl) amino)-1-(4-m

AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES

Compounds are provided that act as potent antagonists of the CCR(9) receptor for treating Sjogren's syndrome. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions.

Heterocyclic compound

The present invention relates to compound (I) or a salt thereof which has a ROR γ t inhibitory action. wherein each symbol is as defined in the specification.