52898-32-5

Basic information

• Product Name: N-(3-BUTEN-1-YL)PHTHALIMIDE
• Synonyms: N-(3-BUTEN-1-YL)PHTHALIMIDE;N-(3-BUTENYL)PHTHALIMIDE;2-(3-BUTENYL)1H-ISOINDOLE-1,3(2H)DIONE;AKOS 345;N-(3-Buten-1-yl)phtalimide;4-Phthalimido-1-butene;N-(3-Buten-1-yl)phthalimide,2-(but-3-enyl)-isoindolin-1,3-dione;2-(3-Butenyl)-2H-isoindole-1,3-dione
• CAS NO: 52898-32-5
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.22
• EINECS: 251-434-4
• Product Categories: N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Phthalimides
• Mol File: 52898-32-5.mol
• Article Data: 58

Chemical Properties

• Melting Point: 52°C
• Boiling Point: 311 °C at 760 mmHg
• Flash Point: 133.3 °C
• Appearance: off-white to white powder
• Density: 1.195g/cm³
• Vapor Pressure: 0.00058mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: 2-8°C
• PKA: -2.14±0.20(Predicted)
• CAS DataBase Reference: N-(3-BUTEN-1-YL)PHTHALIMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-BUTEN-1-YL)PHTHALIMIDE(52898-32-5)
• EPA Substance Registry System: N-(3-BUTEN-1-YL)PHTHALIMIDE(52898-32-5)

Safety Data

• Hazardous Substances Data: 52898-32-5(Hazardous Substances Data)

Usage

Chemical Properties

off-white to white powder

InChI:InChI=1/C12H11NO2/c1-2-3-8-13-11(14)9-6-4-5-7-10(9)12(13)15/h2,4-7H,1,3,8H2

Upstream product

• 136918-14-4 phthalimide 
• 627-27-0 homoalylic alcohol 
• 31645-84-8 N-(4-Chlor-2-butenyl)-phthalimid 
• 1074-82-4 potassium phtalimide 
• 17564-64-6 N-(chloromethyl)phthalimide 
• 203255-55-4 2-(iodomethyl)isoindoline-1,3-dione 
• 106-95-6 allyl bromide 
• 118-29-6 2-(hydroxymethyl)-1H-isoindole-1,3(2H)-dione 
• 14396-90-8 N-(3-butynyl)phthalimide 
• 1609486-16-9 (E)-2-(4-(triethoxysilyl)but-3-enyl)isoindoline-1,3-dione 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 40671-34-9 4-methanesulfonyloxy-1-butene 
• 524-38-9 N-hydroxyphthalimide 
• 5162-44-7 1-bromo-4-butene 

Downstream Products

• 17875-18-2 but-3-en-1-amine hydrochloride 
• 86506-70-9 rac-2-(2-(oxiran-2-yl)ethyl)isoindoline-1,3-dione 
• 476193-24-5 C₂₈H₃₃NO₇S 
• 1152033-10-7 2-(but-3-enyl)-3-(difluoro(phenylsulfanyl)methyl)-3-hydroxyisoindolin-1-one 
• 1350431-03-6 C₂₅H₂₁NO₃ 
• 1350431-09-2 2-(3-(3-(trifluoromethyl)benzyl)but-3-enyl)isoindoline-1,3-dione 
• 1356010-15-5 2-(3-hydroxy-4-(2-(3-methyl-1H-1,2,4-triazol-1-yl)-5-nitrophenoxy)butylcarbamoyl)benzoic acid 
• 1356010-16-6 2-(3-hydroxy-4-(2-(3-methyl-1H-1,2,4-triazol-1-yl)-5-nitrophenoxy)butyl)isoindoline-1,3-dione 
• 143741-67-7 N-(4-phenyl-3-butenyl)phthalimide 

Relevant articles and documents

A Convenient Synthesis of 3-Butenylamine

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Determination of covalently bound hypusine and deoxyhypusine to protein using submilligram of protein samples by HPLC

A sensitive and reliable method for the determination of hypusine and deoxyhypusine in elF-5A protein, an initiation factor of protein synthesis, was developed. An advantage of this method is the use of N(ε)-(5- aminopentyl)lysine, an analogue of deoxyhyp

Electrochemical Synthesis of Allylic Amines from Terminal Alkenes and Secondary Amines

Allylic amines are valuable synthetic targets en route to diverse biologically active amine products. Current allylic C-H amination strategies remain limited with respect to the viable N-substituents. Herein, we disclose a new electrochemical process to p

Pd-Catalyzed Remote Site-Selective and Stereoselective C(Alkenyl)-H Alkenylation of Unactivated Cycloalkenes

A palladium-catalyzed alkenylation involving remote δ-position C(alkenyl)-H activation of cycloalkenes reacting with electron-deficient alkenes is described. This method features excellent site selectivity and stereoselectivity to efficiently afford only E-selective highly substituted 1,3-diene derivatives with extra-ligand-free and good functional group tolerance including estrone and free N-H tryptamine under weakly alkaline conditions. Mechanistic studies suggest that picolinamide as a bidentate directing group enables the formation of unique alkenyl palladacycle intermediates.

Photochemical Decarboxylative C(sp3)-X Coupling Facilitated by Weak Interaction of N-Heterocyclic Carbene

While N-hydroxyphthalimide (NHPI) ester has emerged as a powerful reagent as an alkyl radical source for a variety of C-C bond formations, the corresponding C(sp3)-N bond formation is still in its infancy. We demonstrate herein transition-metal-free decarboxylative C(sp3)-X bond formation enabled by the photochemical activity of the NHPI ester-NaI-NHC complex, giving primary C(sp3)-(N)phth, secondary C(sp3)-I, or tertiary C(sp3)-(meta C)phth coupling products. The primary C(sp3)-(N)phth coupling offers convenient access to primary amines.