52900-79-5

Basic information

• Product Name: 2,3-furandicarboxylic acid dimethyl ester
• Synonyms: 2,3-furandicarboxylic acid dimethyl ester;2,3-Furandicarboxylic acid, 2,3-dimethyl ester;2,3-Dimethyl furan-2,3-dicarboxylate;dimethyl furan-2,3-dicarboxylate;Furan-2,3-dicarboxylic acid dimethyl ester
• CAS NO: 52900-79-5
• Molecular Formula: C₈H₈O₅
• Molecular Weight: 184.14612
• Mol File: 52900-79-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-furandicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-furandicarboxylic acid dimethyl ester(52900-79-5)
• EPA Substance Registry System: 2,3-furandicarboxylic acid dimethyl ester(52900-79-5)

Safety Data

• Hazardous Substances Data: 52900-79-5(Hazardous Substances Data)

Usage

Main properties

1. Chemical compound
2. Molecular formula: C8H8O5
3. Colorless liquid
4. Fruity odor
5. Precursor in polymer production
6. Renewable and biodegradable
7. Valuable compound for sustainable products
8. Potential applications in pharmaceutical and food industries
9. Biocompatible
10. Low toxicity

Specific content

Also known as dimethyl 2,3-furandicarboxylate
Used as a building block for renewable and biodegradable materials
Important in the development of sustainable products
Potential applications in pharmaceutical and food industries
Has a fruity odor
Colorless liquid
Valuable for its unique structure and properties

Upstream product

• 67-56-1 methanol 
• 88-14-2 2-furanoic acid 
• 124-38-9 carbon dioxide 
• 186581-53-3 diazomethane 
• 17640-15-2 methyl cyanoformate 
• 61736-76-3 2-Oxabicyclo<3.2.0>hept-3-en-1,5-dicarbonsaeure-dimethylester 
• 61846-10-4 7-Oxabicyclo<4.1.0>hept-4-en-1,4-dicarbonsaeure-dimethylester 

Downstream Products

• 13379-61-8 furan-2,3-dicarboxylic acid dihydrazide 
• 332013-51-1 4-(4-methoxyphenylamino)-7-chlorofuro-[2,3-d]pyridazine 
• 332013-40-8 4-chloroanilino-7-chlorofuro[2,3-d]pyridazine 
• 332013-41-9 4-chloro-7-[N-(4-chlorophenyl)amino]-[2,3-d]furopyridazine 
• 332012-46-1 4-[({4-[(4-methoxyphenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methyl-2-pyridinecarboxamide 
• 332012-40-5 Telatinib 
• 332012-41-6 4-(4-chlorophenylamino)-2-methylaminocarbonyl-7-(2-methylaminocarbonyl-4-pyridylmethoxy)-furo[2,3-d]pyridazine 
• 332012-57-4 4-[({4-[(3-chlorophenyl)amino]-furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methyl-2-pyridinecarboxamide 
• 13177-71-4 5,6-dihydrofuro[2,3-d]pyridazine-4,7-dione 
• 13177-70-3 4,7-dichlorofuro[2,3-d]pyridazine 
• 271-93-2 Furo<2,3-d>pyridazin 
• 770-07-0 5-nitro-furan-3-carboxylic acid 

Relevant articles and documents

One-step synthesis of furan-2,5-dicarboxylic acid from furan-2-carboxylic acid using carbon dioxide

A short and effective method for preparation and isolation of furan-2,5-dicarboxylic acid has been developed. Furan-2,5-dicarboxylic acid was prepared directly from furan-2-carboxylic acid in one step under strong basic conditions using carbon dioxide. This method allows to obtain the product with high added value, furan-2,5-dicarboxylic acid, from natural sources such as hemicelluloses containing pentoses. ARKAT-USA, Inc.

Synthese, Thermolyse und Photolyse substituierter 3,4-Epoxy-cycloalkene

The substituted epoxy-cycloalkenes 5 - 7 are transformed thermally at 200 - 250 deg C into the benzene derivatives 10, 15, and 18 after initial C/O-bond cleavage of the oxirane ring.At temperatures higher than 300 deg C (short time pyrolysis) 6 and 7 give, in addition to the aromatic compounds 15/18, the furans 16 and 19, respectively.On photochemical excitation 5 - 7 react with C/C-ring opening to the annelated 2,3-dihydrofurans 11, 17, and 20, respectively.The epoxycycloheptene 8 undergoes analogous ring expansion leading to 21 on electronic as well as thermal activation (ca. 80percent yield).Whereas 21 does not form any defined product up to 380 deg C, and the monosubstituted bicyclus 11 suffers fragmentation affording methyl 3-furancarboxylate (12) and ethylene, both dihydrofurans 17 and 20 are quantitatively converted back into the epoxy-cycloalkenes 6 and 7, respectively, at temperatures below 200 deg C; the cycloreversion reaction affording 16/19 competes only above 300 deg C.The cyclic dipoles of type IV, assumed to occur as intermediates during the 2,3-dihydrofuran-vinyloxirane isomerisations 17 . 6/20 . 7, can be trapped with dimethyl acetylenedicarboxylate or N-phenylmaleimide at significantly lower temperature (150/120 deg C) to give the 1:1-cycloadducts 38 - 40.However, because no such products could be obtained in case of the photoreactions of 5 - 8, a concerted -C-migration has to be considered as a mechanistic alternative of the light-induced formation of 11, 17, 20, and 21.