53042-33-4 Usage
Description
Lithium dimethylaminoborohydride (1M solution in tetrahydrofuran, THF) is a versatile reagent that exhibits dual properties of a metal hydride and a nitrogen nucleophile. It is often considered as an alternative to lithium aluminum hydride (LAH) for the reduction of various functional groups, including carbonyl compounds, amides, and lactams. This reagent is particularly useful in organic synthesis due to its unique combination of reactivity and selectivity.
Uses
Used in Organic Synthesis:
Lithium dimethylaminoborohydride is used as a reducing agent for the selective reduction of various functional groups, such as carbonyl compounds, amides, and lactams. Its dual properties as a metal hydride and nitrogen nucleophile make it a valuable tool in organic synthesis, offering unique reactivity and selectivity compared to other reducing agents.
Used in B-H Oxidative Addition Reactions:
In this application, lithium dimethylaminoborohydride serves as a key reactant in B-H oxidative addition reactions, which are important for the formation of new chemical bonds and the synthesis of complex organic molecules.
Used in Reduction and Amination Reactions:
This reagent is also utilized in reduction and amination reactions, where it facilitates the conversion of one functional group to another, often with high selectivity and efficiency.
Used in the Synthesis of Tertiary Amine-Boranes:
Lithium dimethylaminoborohydride is employed in the synthesis of tertiary amine-boranes, which are valuable intermediates in organic chemistry and can be used for further functionalization and modification of organic molecules.
Used in the Reduction of N-alkyl Lactams:
The reagent is also used for the reduction of N-alkyl lactams, which are important structural motifs in various biologically active compounds and pharmaceuticals. The reduction of these lactams can lead to the formation of valuable building blocks for the synthesis of complex molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 53042-33-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,0,4 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 53042-33:
(7*5)+(6*3)+(5*0)+(4*4)+(3*2)+(2*3)+(1*3)=84
84 % 10 = 4
So 53042-33-4 is a valid CAS Registry Number.
