53155-11-6

Basic information

• Product Name: (Z)-1-Bromo-3-octene
• Synonyms: (Z)-1-Bromo-3-octene
• CAS NO: 53155-11-6
• Molecular Formula: C₈H₁₅Br
• Molecular Weight: 191.11
• Mol File: 53155-11-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 198.4°C at 760 mmHg
• Flash Point: 70.4°C
• Appearance: /
• Density: 1.141g/cm³
• Vapor Pressure: 0.508mmHg at 25°C
• Refractive Index: 1.472
• CAS DataBase Reference: (Z)-1-Bromo-3-octene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1-Bromo-3-octene(53155-11-6)
• EPA Substance Registry System: (Z)-1-Bromo-3-octene(53155-11-6)

Safety Data

• Hazardous Substances Data: 53155-11-6(Hazardous Substances Data)

Usage

General Description

(Z)-1-Bromo-3-octene is a chemical compound with the molecular formula C8H15Br. It is an alkene with a bromine atom attached to the first carbon of the double bond, resulting in a unique geometric isomerism. (Z)-1-Bromo-3-octene is commonly used as a synthetic intermediate in organic chemistry, particularly in the production of pharmaceuticals and agrochemicals. It is also used in the manufacturing of fine chemicals and as a building block in the synthesis of complex organic molecules. (Z)-1-Bromo-3-octene is known for its reactivity and versatility, making it a valuable compound in the field of chemical synthesis and research.

InChI:InChI=1/C8H15Br/c1-2-3-4-5-6-7-8-9/h5-6H,2-4,7-8H2,1H3/b6-5-

Upstream product

• 693-02-7 hex-1-yne 
• 288591-17-3 (Z)-oct-3-enyl methanesulfonate 
• 14916-80-4 oct-3-yn-1-ol 
• 85217-50-1 2-(3-octyn-1-yloxy)tetrahydro-2H-pyran 
• 160436-23-7 (Z)-2-(3-octen-1-yloxy)tetrahydro-2H-pyran 
• 111789-39-0 (Z)-oct-3-enyl 4-methylbenzenesulfonate 
• 18185-81-4 cis-3-octen-1-ol 

Downstream Products

• 18185-81-4 cis-3-octen-1-ol 
• 16725-53-4 (Z)-9-tetradecen-1-yl acetate 
• 35153-15-2 (Z)-9-tetradecen-1-ol 
• 71612-09-4 (Z)-1-(2-Tetrahydropyranyloxy)-9-tetradecene 
• 53963-06-7 Z,Z-7,11-hexadecadienyl alcohol 
• 52207-99-5 (7Z,11Z)-7,11-hexadecadien-1-yl acetate 
• 69668-83-3 (3Z)?3-octenyl acetate 

Relevant articles and documents

Natural trienoic acids as anticancer agents: First stereoselective synthesis, cell cycle analysis, induction of apoptosis, cell signaling and mitochondrial targeting studies

The first Z-stereoselective method was developed for the synthesis of unsaturated acids containing a 1Z,5Z,9Z-triene moiety in 61–64% yields using the new Ti-catalyzed cross-coupling of oxygen-containing and aliphatic 1,2-dienes as the key synthetic step. It was shown for the first time that trienoic acids with non-methylene-interrupted Z-double bonds show moderate cytotoxic activities against tumor cell lines (Jurkat, K562, U937, HL60, HeLa), human embryonic kidney cells (Hek293), normal fibroblasts and human topoisomerase I (hTop1) inhibitory activity in vitro. The synthesized acids efficiently initiate apoptosis of Jurkat tumor cells, with the cell death mechanism being activated by the mitochondrial pathway. A probable mechanism of topoisomerase I inhibition was also hypothesized on the basis of in silico studies resorting to docking. The activation and inhibition of the most versatile intracellular signaling pathways (CREB, JNK, NFkB, p38, ERK1/2, Akt, p70S6K, STAT3 and STAT5 tyrosine kinases) responsible for cell proliferation and for initiation of apoptosis were studied by multiplex assay technology (Luminex xMAP).

Chain-modified pyridino-N substituted nicotine compounds for use in the treatment of CNS pathologies

Compounds for treating abuse of nicotinic receptor agonists, addiction to psychostimulant drugs, addiction to opiates, addiction to alcohol, addiction to tobacco products, addiction to nicotine, schizophrenia and related diseases, depression and related conditions, Alzheimer's disease, Parkinson's disease, irritable bowel syndrome, and colitis. The compounds competitively inhibit central nervous system acting nicotinic receptor agonists and act at the putative α3β2* and α4β2 neuronal nicotinic receptors in the central nervous system.

An efficient and stereoselective synthesis of insect pheromones by way of nickel-catalyzed Grignard reactions. Syntheses of gossyplure and pheromones of Eudia pavonia and Droxophila melanogaster

Three pheromones, (6Z,11Z)-hexadeca-6,11-dien-1-yl acetate (from Eudia pavonia), (5Z,9Z)-heptacosa-5,9-diene (from Drosophila melanogaster) and gossyplure, have been synthesized each by two consecutive consequences of nickel-assisted Grignard reactions with cyclic enol ethers and preparation of Grignard reagents from the resultant alcohols.